Gadolinium deposition in the brain: summary of evidence and recommendations
Emerging evidence has linked MRI signal changes in deep nuclei of the brain with repeated
administration of gadolinium-based contrast agents. Gadolinium deposits have been …
administration of gadolinium-based contrast agents. Gadolinium deposits have been …
Gadolinium deposition in the brain: current updates
JW Choi, WJ Moon - Korean journal of radiology, 2019 - synapse.koreamed.org
Gadolinium-based contrast agents (GBCAs) are commonly used for enhancement in MR
imaging and have long been considered safe when administered at recommended doses …
imaging and have long been considered safe when administered at recommended doses …
The presence of the gadolinium-based contrast agent depositions in the brain and symptoms of gadolinium neurotoxicity-A systematic review
Background and purpose Gadolinium based contrast agents (GBCAs) are widely used in
magnetic resonance imaging, but recently, high signal intensity in the cerebellum structures …
magnetic resonance imaging, but recently, high signal intensity in the cerebellum structures …
Assessing treatment outcomes in multiple sclerosis trials and in the clinical setting
Increasing numbers of drugs are being developed for the treatment of multiple sclerosis
(MS). Measurement of relevant outcomes is key for assessing the efficacy of new drugs in …
(MS). Measurement of relevant outcomes is key for assessing the efficacy of new drugs in …
Penetration and distribution of gadolinium-based contrast agents into the cerebrospinal fluid in healthy rats: a potential pathway of entry into the brain tissue
G Jost, T Frenzel, J Lohrke, DC Lenhard… - European …, 2017 - Springer
Objective Signal hyperintensity on unenhanced MRI in certain brain regions has been
reported after multiple administrations of some, but not all, gadolinium-based contrast …
reported after multiple administrations of some, but not all, gadolinium-based contrast …
Ten years of gadolinium retention and deposition: ESMRMB-GREC looks backward and forward
AJ van der Molen, CC Quattrocchi, CA Mallio… - European …, 2024 - Springer
In 2014, for the first time, visible hyperintensities on unenhanced T1-weighted images in the
nucleus dentatus and globus pallidus of the brain were associated with previous Gadolinium …
nucleus dentatus and globus pallidus of the brain were associated with previous Gadolinium …
No signal intensity increase in the dentate nucleus on unenhanced T1-weighted MR images after more than 20 serial injections of macrocyclic gadolinium-based …
Purpose To determine the effect of more than 20 serial injections of macrocyclic gadolinium-
based contrast agents (GBCAs) on the signal intensity (SI) of the dentate nucleus (DN) on …
based contrast agents (GBCAs) on the signal intensity (SI) of the dentate nucleus (DN) on …
Gadolinium retention and toxicity—an update
Until 2006, the main considerations regarding safety for all gadolinium-based contrast
agents (GBCAs) were related to short-term adverse reactions. However, the administration …
agents (GBCAs) were related to short-term adverse reactions. However, the administration …
Quantifying iron content in magnetic resonance imaging
K Ghassaban, S Liu, C Jiang, EM Haacke - Neuroimage, 2019 - Elsevier
Measuring iron content has practical clinical indications in the study of diseases such as
Parkinson's disease, Huntington's disease, ferritinopathies and multiple sclerosis as well as …
Parkinson's disease, Huntington's disease, ferritinopathies and multiple sclerosis as well as …
Prospective T1 mapping to assess gadolinium retention in brain after intrathecal gadobutrol
G Ringstad, LM Valnes, SAS Vatnehol, AH Pripp… - Neuroradiology, 2023 - Springer
Purpose A possible pathway behind gadolinium retention in brain is leakage of contrast
agents from blood to cerebrospinal fluid and entry into brain along perivascular (glymphatic) …
agents from blood to cerebrospinal fluid and entry into brain along perivascular (glymphatic) …