Our recent progress in epigenetic research using the model ciliate, Tetrahymena thermophila
Epigenetic research focuses on heritable changes beyond the DNA sequence, which has
led to a revolution in biological studies and benefits in many other fields. The well-known …
led to a revolution in biological studies and benefits in many other fields. The well-known …
The completed macronuclear genome of a model ciliate Tetrahymena thermophila and its application in genome scrambling and copy number analyses
Y Sheng, L Duan, T Cheng, Y Qiao, NA Stover… - Science China Life …, 2020 - Springer
The ciliate Tetrahymena thermophila has been a powerful model system for molecular and
cellular biology. However, some investigations have been limited due to the incomplete …
cellular biology. However, some investigations have been limited due to the incomplete …
N6-methyladenine DNA modification in the unicellular eukaryotic organism Tetrahymena thermophila
Abstract N 6-methyladenine DNA (6mA) modification exists in both prokaryotes and
eukaryotes in which it plays a crucial role in regulating numerous biological processes. In …
eukaryotes in which it plays a crucial role in regulating numerous biological processes. In …
N6-adenine DNA methylation is associated with the linker DNA of H2A.Z-containing well-positioned nucleosomes in Pol II-transcribed genes in Tetrahymena
Abstract DNA N6-methyladenine (6mA) is newly rediscovered as a potential epigenetic mark
across a more diverse range of eukaryotes than previously realized. As a unicellular model …
across a more diverse range of eukaryotes than previously realized. As a unicellular model …
Further analyses of variation of ribosome DNA copy number and polymorphism in ciliates provide insights relevant to studies of both molecular ecology and phylogeny
Y Wang, C Wang, Y Jiang, LA Katz, F Gao… - Science China Life …, 2019 - Springer
Sequence-based approaches, such as analyses of ribosome DNA (rDNA) clone libraries
and high-throughput amplicon sequencing, have been used extensively to infer evolutionary …
and high-throughput amplicon sequencing, have been used extensively to infer evolutionary …
Comprehensive genome annotation of the model ciliate Tetrahymena thermophila by in-depth epigenetic and transcriptomic profiling
The ciliate Tetrahymena thermophila is a well-established unicellular model eukaryote,
contributing significantly to foundational biological discoveries. Despite its acknowledged …
contributing significantly to foundational biological discoveries. Despite its acknowledged …
Genome analyses of the new model protist Euplotes vannus focusing on genome rearrangement and resistance to environmental stressors
X Chen, Y Jiang, F Gao, W Zheng… - Molecular ecology …, 2019 - Wiley Online Library
As a model organism for studies of cell and environmental biology, the free‐living and
cosmopolitan ciliate Euplotes vannus shows intriguing features like dual genome …
cosmopolitan ciliate Euplotes vannus shows intriguing features like dual genome …
Dynamic DNA N6-adenine methylation (6mA) governs the encystment process, showcased in the unicellular eukaryote Pseudocohnilembus persalinus
Y Liu, J Niu, F Ye, T Solberg, B Lu, C Wang… - Genome …, 2024 - genome.cshlp.org
The formation of resting cysts commonly found in unicellular eukaryotes is a complex and
highly regulated survival strategy against environmental stress that involves drastic …
highly regulated survival strategy against environmental stress that involves drastic …
A distinct class of eukaryotic MT-A70 methyltransferases maintain symmetric DNA N6-adenine methylation at the ApT dinucleotides as an epigenetic mark associated …
Y Wang, Y Sheng, Y Liu, W Zhang, T Cheng… - Nucleic acids …, 2019 - academic.oup.com
Rediscovered as a potential eukaryotic epigenetic mark, DNA N6-adenine methylation
(6mA) varies across species in abundance and its relationships with transcription. Here we …
(6mA) varies across species in abundance and its relationships with transcription. Here we …
Phylogenetic relationship analyses of complicated class Spirotrichea based on transcriptomes from three diverse microbial eukaryotes: Uroleptopsis citrina, Euplotes …
Y Sheng, M He, F Zhao, C Shao, M Miao - Molecular phylogenetics and …, 2018 - Elsevier
Ciliates are one of the eukaryotic unicellular organisms which are thought to be the oldest
life forms, and widely geographically distributed. For a variety of reasons, some groups of …
life forms, and widely geographically distributed. For a variety of reasons, some groups of …