Cardiovascular diseases (CVDs) are one of the leading causes of the most considerable
mortality globally, and it has been tried to find the molecular mechanisms and design new …

Mass spectrometry–based quantitative proteomics is a powerful tool for gaining insights into
function and dynamics of biological systems. However, peptides with different sequences …

Nuclear factor kappa B (NF-κB) signaling pathways progress inflammation and immune cell
differentiation in the host immune response; however, the uncontrollable stimulation of NF …

The mammalian immune system is optimized to cope effectively with the constant threat of
pathogens. However, when the immune system overreacts, sepsis, severe sepsis, or septic …

Lucidone, which comprises a naturally occurring cyclopentenedione, has been investigated
for its in vitro and in vivo wound healing properties, and the underlying molecular signaling …

Abstract Sirtuin 2 (SIRT 2) is a member of the sirtuin family of NAD+‐dependent protein
deacetylases. In recent years, SIRT 2 inhibition has emerged as a promising treatment for …

As major effector cells of the innate immune response, macrophages must adeptly migrate
from blood to infected tissues. Endothelial transmigration is accomplished by matrix …

Diallyl disulfide (DADS) is a major organosulfur compound found in garlic oil that is widely
used as a flavoring agent. In this study, we evaluated the effects of DADS on airway …

Statins are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors used
worldwide to manage dyslipidaemia and thus limit the development of atherosclerotic …

Background/Aims: Obese individuals are known to have increased Matrix metalloproteinase
(MMP)-9 plasma levels and MMP-9 is reported to play an important role in obesity …