Bladder infections affect millions of people yearly, and recurrent symptomatic infections (cystitis) are very common. The rapid increase in infections caused by multidrug-resistant …
Urinary tract infections (UTI) are one of the most common bacterial infections, with roughly eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …
This is the second edition of our little red book Lectins published in 1989. In the intervening years well over 10,000 articles have appeared with lectins as the main subject, and more …
The first step in the colonization of the human urinary tract by pathogenic Escherichia coli is the mannose‐sensitive binding of FimH, the adhesin present at the tip of type 1 pili, to the …
The chaperone–usher (CU) pathway of pilus biogenesis is the most widespread of the five pathways that assemble adhesive pili at the surface of Gram-negative bacteria. Recent …
I Vallet, JW Olson, S Lory… - Proceedings of the …, 2001 - National Acad Sciences
Pseudomonas aeruginosa, an important opportunistic human pathogen, persists in certain tissues in the form of specialized bacterial communities, referred to as biofilm. The biofilm is …
SP Nuccio, AJ Bäumler - Microbiology and Molecular Biology …, 2007 - Am Soc Microbiol
Many Proteobacteria use the chaperone/usher pathway to assemble proteinaceous filaments on the bacterial surface. These filaments can curl into fimbrial or nonfimbrial …
JS Pinkner, H Remaut, F Buelens… - Proceedings of the …, 2006 - National Acad Sciences
A chemical synthesis platform with broad applications and flexibility was rationally designed to inhibit biogenesis of adhesive pili assembled by the chaperone–usher pathway in Gram …
Vibrio cholerae is a bacterial pathogen that colonizes the chitinous exoskeleton of zooplankton as well as the human gastrointestinal tract. Colonization of these different …