The cause of insulin resistance in obesity and type 2 diabetes mellitus (T2DM) is not limited
to impaired insulin signalling but also involves the complex interplay of multiple metabolic …

Triacylglycerols (TAG) serve as the predominant form of energy storage in mammalian cells,
and TAG synthesis influences conditions such as obesity, fatty liver, and insulin resistance …

Typical formulated broiler diets are deficient in n-3 poly-unsaturated fatty acids (PUFA) due
to widening n-6: n-3 PUFA ratio which could greatly affect performance, immune system of …

Obesity is characterized by excessive fatty acid conversion to triacylglycerols (TAGs) in
adipose tissues. However, how signaling networks sense fatty acids and connect to the …

Phosphatidic acid (PA) is a glycerophospholipid intermediate in the triglyceride synthesis
pathway that has incredibly important structural functions as a component of cell membranes …

Objective Both obesity and exposure to chemicals may induce non-alcoholic fatty liver
disease (NAFLD). Pregnane X Receptor (PXR) is a central target of metabolism disrupting …

Cancer cells reprogram their metabolism to increase the synthesis of macromolecules for
rapid proliferation. Compared to fatty acids, much less is known about the synthesis of …

This study concerns obesity-related atherosclerosis, hyperlipidemia, and chronic
inflammation. We studied the anti-obesity and anti-atherosclerosis effects of phenethyl …

Objective—Macrophage proinflammatory responses induced by modified low-density
lipoproteins (modLDL) contribute to atherosclerotic progression. How modLDL causes …

Lipin 1 regulates glycerolipid homeostasis by acting as a phosphatidic acid
phosphohydrolase (PAP) enzyme in the triglyceride-synthesis pathway and by regulating …