[PDF][PDF] Somatic cell nuclear transfer: failures, successes and the challenges ahead

M Czernik, DA Anzalone, L Palazzese… - The International …, 2019 - scholar.archive.org
Somatic cell nuclear transfer (SCNT) has a broad spectrum of potential applications,
including rescue of endangered species, production of transgenic animals, drug production …

Porcine uterine luminal fluid-derived extracellular vesicles improve conceptus-endometrial interaction during implantation

Q Hu, X Zang, Y Ding, T Gu, J Shi, Z Li, G Cai, D Liu… - Theriogenology, 2022 - Elsevier
Successful implantation of porcine conceptus requires synergistic interaction with various
signal molecules in the maternal uterus. Extracellular vesicles (EVs) in uterine luminal fluid …

哺乳动物体细胞核移植表观遗传重编程研究进展

杨旭琼, 吴珍芳, 李紫聪 - 遗传, 2019 - chinagene.cn
体细胞核移植(somatic cell nuclear transfer, SCNT) 是唯一能赋予体细胞基因组全能性的生殖
工程技术, 对动物种质资源保存, 畜牧业发展和生物医学研究等具有重大意义 …

Improvement of developmental competence of cloned male pig embryos by short hairpin ribonucleic acid (shRNA) vector-based but not small interfering RNA (siRNA) …

X Yang, X Wu, Y Yang, T Gu, L Hong… - … of Reproduction and …, 2019 - jstage.jst.go.jp
Xist is an X-linked ribonucleic acid (RNA) gene responsible for the cis induction of X
chromosome inactivation (XCI). In cloned mammalian embryos, Xistis ectopically activated …

Knockdown of RLIM inhibits XIST expression and improves developmental competence of cloned male pig embryos

L Yang, X Wu, N Zhang, J Shi, R Zhou… - Molecular …, 2021 - Wiley Online Library
Ectopic expression of Xist on the putative active X chromosome is a primary cause of the low
developmental efficiency of cloned mouse and pig embryos. Suppression of abnormal Xist …