Mycotoxins co-contamination: Methodological aspects and biological relevance of combined toxicity studies

I Alassane-Kpembi, G Schatzmayr… - Critical Reviews in …, 2017 - Taylor & Francis
Mycotoxins are secondary fungal metabolites produced mainly by Aspergillus, Penicillium,
and Fusarium. As evidenced by large-scale surveys, humans and animals are …

Fumonisin B1: Mechanisms of toxicity and biological detoxification progress in animals

J Chen, Z Wei, Y Wang, M Long, W Wu… - Food and chemical …, 2021 - Elsevier
Abstract Fumonisin B1 (FB 1) is a toxic secondary metabolite produced by the Fusarium
molds that can contaminate food and feed. It has been found that FB 1 can cause systemic …

Risks to human and animal health related to the presence of deoxynivalenol and its acetylated and modified forms in food and feed

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2017 - Wiley Online Library
Deoxynivalenol (DON) is a mycotoxin primarily produced by Fusarium fungi, occurring
predominantly in cereal grains. Following the request of the European Commission, the …

Impact of mycotoxins on the intestine: are mucus and microbiota new targets?

H Robert, D Payros, P Pinton, V Theodorou… - Journal of Toxicology …, 2017 - Taylor & Francis
There is an increasing awareness of the deleterious effects attributed to mycotoxins during
their fate within the gut, particularly for deoxynivalenol (DON), zearalenone (ZEN) …

Mycotoxin exposure in rural residents in northern Nigeria: A pilot study using multi-urinary biomarkers

CN Ezekiel, B Warth, IM Ogara, WA Abia… - Environment …, 2014 - Elsevier
A pilot, cross-sectional, correlational study was conducted in eight rural communities in
northern Nigeria to investigate mycotoxin exposures in 120 volunteers (19 children, 20 …

Deoxynivalenol alone or in combination with nivalenol and zearalenone induce systemic histological changes in pigs

JR Gerez, P Pinton, P Callu, F Grosjean… - Experimental and …, 2015 - Elsevier
Abstract Deoxynivalenol (DON), nivalenol (NIV) and zearalenone (ZEA) are mycotoxins
commonly produced by Fusarium species. The purpose of the present study was to …

Protective capacity of resveratrol, a natural polyphenolic compound, against deoxynivalenol-induced intestinal barrier dysfunction and bacterial translocation

KH Ling, MLY Wan, H El-Nezami… - Chemical Research in …, 2016 - ACS Publications
Contamination of food/feedstuffs by mycotoxins is a serious problem worldwide, causing
severe economic losses and serious health problems in animals/humans. Deoxynivalenol …

Individual and combined cytotoxic effects of aflatoxin B1, zearalenone, deoxynivalenol and fumonisin B1 on BRL 3A rat liver cells

LH Sun, M Lei, NY Zhang, X Gao, C Li, CS Krumm… - Toxicon, 2015 - Elsevier
This study was performed to determine the individual and combined cytotoxic effects of
Aflatoxin B 1 (AFB 1), zearalenone (ZEA), deoxynivalenol (DON) and fumonisin B 1 (FB 1) …

Low doses of individual and combined deoxynivalenol and zearalenone in naturally moldy diets impair intestinal functions via inducing inflammation and disrupting …

R Jia, W Liu, L Zhao, L Cao, Z Shen - Toxicology letters, 2020 - Elsevier
The intestinal epithelium is the first barrier against food contaminants and is highly sensitive
to Fusarium toxins, especially deoxynivalenol (DON) and zearalenone (ZEA). Here, we …

Bio-monitoring of mycotoxin exposure in Cameroon using a urinary multi-biomarker approach

WA Abia, B Warth, M Sulyok, R Krska, A Tchana… - Food and chemical …, 2013 - Elsevier
Bio-monitoring of human exposure to mycotoxin has mostly been limited to a few individually
measured mycotoxin biomarkers. This study aimed to determine the frequency and level of …