Tendon healing is adversely affected by low-grade inflammation

E Chisari, L Rehak, WS Khan, N Maffulli - Journal of Orthopaedic Surgery …, 2021 - Springer
Background Tendinopathy is common, presents with pain and activity limitation, and is
associated with a high risk of recurrence of the injury. Tendinopathy usually occurs as a …

Cytokines in tendon disease: a systematic review

W Morita, SG Dakin, SJB Snelling… - Bone & joint …, 2017 - boneandjoint.org.uk
Objectives Emerging evidence indicates that tendon disease is an active process with
inflammation that is critical to disease onset and progression. However, the key cytokines …

Intratendon delivery of leukocyte-poor platelet-rich plasma improves healing compared with leukocyte-rich platelet-rich plasma in a rabbit Achilles tendinopathy model

R Yan, Y Gu, J Ran, Y Hu, Z Zheng… - … American journal of …, 2017 - journals.sagepub.com
Background: Chronic tendinopathy is a commonly occurring clinical problem that affects
both athletes and inactive middle-aged patients. Although some studies have shown that …

Tendon healing in presence of chronic low-level inflammation: a systematic review

E Chisari, L Rehak, WS Khan… - British Medical Bulletin, 2019 - academic.oup.com
Background Tendinopathy is a common musculoskeletal condition affecting subjects
regardless of their activity level. Multiple inflammatory molecules found in ex vivo samples of …

[HTML][HTML] Inflammatory mechanisms linking obesity and tendinopathy

PPY Lui, PSH Yung - Journal of Orthopaedic Translation, 2021 - Elsevier
Chronic tendinopathy is a debilitating tendon disorder with disappointing treatment
outcomes. This review focuses on the potential roles of chronic low-grade inflammation in …

Osteopathy in complex lymphatic anomalies

E Solorzano, AL Alejo, HC Ball, J Magoline… - International Journal of …, 2022 - mdpi.com
Complex Lymphatic Anomalies (CLA) are lymphatic malformations with idiopathic bone and
soft tissue involvement. The extent of the abnormal lymphatic presentation and boney …

Decreased grip strength, muscle pain, and atrophy occur in rats following long‐term exposure to excessive repetitive motion

M Fujiwara, M Iwata, T Inoue, Y Aizawa… - FEBS open …, 2017 - Wiley Online Library
Work‐related musculoskeletal disorders (WMSD) are caused by the overuse of muscles in
the workplace. Performing repetitive tasks is a primary risk factor for the development of …

Tendinopathy and tendon material response to load: What we can learn from small animal studies

PM Williamson, BR Freedman, N Kwok, I Beeram… - Acta biomaterialia, 2021 - Elsevier
Tendinopathy is a debilitating disease that causes as much as 30% of all musculoskeletal
consultations. Existing treatments for tendinopathy have variable efficacy, possibly due to …

Blocking substance P signaling reduces musculotendinous and dermal fibrosis and sensorimotor declines in a rat model of overuse injury

MF Barbe, BA Hilliard, PW Fisher… - Connective tissue …, 2020 - Taylor & Francis
ABSTRACT Purpose/Aim: Substance P-NK-1R signaling has been implicated in fibrotic
tendinopathies and myositis. Blocking this signaling with a neurokinin 1 receptor antagonist …

Prolonged high force high repetition pulling induces osteocyte apoptosis and trabecular bone loss in distal radius, while low force high repetition pulling induces bone …

MF Barbe, VS Massicotte, S Assari, MA Monroy… - Bone, 2018 - Elsevier
We have an operant rat model of upper extremity reaching and grasping in which we
examined the impact of performing a high force high repetition (High-ForceHR) versus a low …