Overview of recent developments of pyrazole derivatives as an anticancer agent in different cell line

FE Bennani, L Doudach, Y Cherrah, Y Ramli… - Bioorganic …, 2020 - Elsevier
Pyrazole is a five-membered aromatic heterocyclic ring with two adjacent nitrogen atoms C 3
H 3 N 2 H. The presence of this nucleus in pharmacological agents of various therapeutic …

The therapeutic voyage of pyrazole and its analogs: a review

MF Khan, MM Alam, G Verma, W Akhtar… - European journal of …, 2016 - Elsevier
Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …

Recent advances in bioactive pyrazoles

ŞG Küçükgüzel, S Şenkardeş - European Journal of Medicinal Chemistry, 2015 - Elsevier
Pyrazole is a five membered and two-nitrogen containing heterocyclic ring. These structures
have been investigated in the development of novel compounds with hypoglycemic …

Anticancer potential of coumarin and its derivatives

N Bhattarai, AA Kumbhar, YR Pokharel… - Mini Reviews in …, 2021 - ingentaconnect.com
Coumarins are found in higher plants like Rutaceae and Umbelliferae and essential oils of
cinnamon bark, cassia leaf, and lavender oil. Coumarin compounds show different …

A review: Biologically active 3, 4-heterocycle-fused coumarins

F Salehian, H Nadri, L Jalili-Baleh… - European Journal of …, 2021 - Elsevier
The combination of heterocycles offers a new opportunity to create novel multicyclic
compounds having improved biological activity. Coumarins are ubiquitous natural …

Coumarin hybrids as novel therapeutic agents

S Sandhu, Y Bansal, O Silakari, G Bansal - Bioorganic & medicinal …, 2014 - Elsevier
Naturally occurring coumarins, having wide spectrum of activities such as antioxidant, anti-
inflammatory, anticancer, MAO-B inhibitory and antimicrobial, are frequently used by the …

Anti-cancer nitrogen-containing heterocyclic compounds

Z Hosseinzadeh, A Ramazani… - Current Organic …, 2018 - benthamdirect.com
Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …

Recent advancement in drug design and discovery of pyrazole biomolecules as cancer and inflammation therapeutics

MJ Alam, O Alam, MJ Naim, F Nawaz, A Manaithiya… - Molecules, 2022 - mdpi.com
Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …

Catalytic Synthesis of 2H-Chromenes

N Majumdar, ND Paul, S Mandal, B de Bruin… - ACS …, 2015 - ACS Publications
2 H-Chromenes (2 H-1-benzopyran derivatives) display a broad spectrum of biological
activities. The 2 H-chromene substructure is an important structural motif present in a variety …

Recent progress in anticancer agents incorporating pyrazole scaffold

S Mor, M Khatri, R Punia… - Mini Reviews in Medicinal …, 2022 - benthamdirect.com
The search for new anticancer agents is considered a dynamic field of medicinal chemistry.
In recent years, the synthesis of compounds with anticancer potential has increased and a …