X-ray-based techniques to study the nano–bio interface

C Sanchez-Cano, RA Alvarez-Puebla, JM Abendroth… - ACS …, 2021 - ACS Publications
X-ray-based analytics are routinely applied in many fields, including physics, chemistry,
materials science, and engineering. The full potential of such techniques in the life sciences …

[HTML][HTML] Perspectives on single particle imaging with x rays at the advent of high repetition rate x-ray free electron laser sources

J Bielecki, FRNC Maia, AP Mancuso - Structural Dynamics, 2020 - pubs.aip.org
X-ray free electron lasers (XFELs) now routinely produce millijoule level pulses of x-ray
photons with tens of femtoseconds duration. Such x-ray intensities gave rise to the idea that …

3D diffractive imaging of nanoparticle ensembles using an x-ray laser

K Ayyer, PL Xavier, J Bielecki, Z Shen, BJ Daurer… - Optica, 2021 - opg.optica.org
Single particle imaging at x-ray free electron lasers (XFELs) has the potential to determine
the structure and dynamics of single biomolecules at room temperature. Two major hurdles …

[PDF][PDF] Bragg coherent diffraction imaging with the CITIUS charge-integrating detector

M Grimes, K Pauwels, TU Schülli, T Martin… - Journal of Applied …, 2023 - journals.iucr.org
The CITIUS detector is a next-generation high-speed X-ray imaging detector. It has
integrating-type pixels and is designed to show a consistent linear response at a frame rate …

Single-image super-resolution improvement of x-ray single-particle diffraction images using a convolutional neural network

A Tokuhisa, Y Akinaga, K Terayama… - Journal of Chemical …, 2022 - ACS Publications
Femtosecond X-ray pulse lasers are promising probes for the elucidation of the
multiconformational states of biomolecules because they enable snapshots of single …

Characterization of 128 Î 128 MM-PAD-2.1 ASIC: a fast framing hard x-ray detector with high dynamic range

D Gadkari, KS Shanks, H Hu, HT Philipp… - Journal of …, 2022 - iopscience.iop.org
We characterize a new x-ray Mixed-Mode Pixel Array Detector (MM-PAD-2.1) Application
Specific Integrated Circuit (ASIC). Using an integrating pixel front-end with dynamic charge …

[HTML][HTML] Expected resolution limits of x-ray free-electron laser single-particle imaging for realistic source and detector properties

Y Kim, J Bielecki, M Sikorski, R de Wijn… - Structural …, 2022 - pubs.aip.org
The unprecedented intensity of x-ray free-electron laser sources has enabled single-particle
x-ray diffraction imaging (SPI) of various biological specimens in both two-dimensional …

European X-ray Free-Electron Laser

MV Kovalchuk, AE Blagov - Crystallography Reports, 2022 - Springer
The review is devoted to the launching of the European X-ray Free Electron Laser (XFEL).
The history of development and operation principles of classical lasers and X-ray free …

[HTML][HTML] Molecular size dependence on achievable resolution from XFEL single-particle 3D reconstruction

M Nakano, O Miyashita, F Tama - Structural Dynamics, 2023 - pubs.aip.org
Single-particle analysis using x-ray free-electron lasers (XFELs) is a novel method for
obtaining structural information of samples in a state close to nature. In particular, it is …

High dynamic range CdTe mixed-mode pixel array detector (MM-PAD) for kilohertz imaging of hard x-rays

HT Philipp, MW Tate, KS Shanks… - Journal of …, 2020 - iopscience.iop.org
A hard x-ray, high-speed, high dynamic range scientific x-ray imager is described. The
imager is based on the mixed-mode pixel array detector (MM-PAD) readout chip coupled to …