Per‐and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research

SE Fenton, A Ducatman, A Boobis… - Environmental …, 2021 - Wiley Online Library
Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …

Consideration of pathways for immunotoxicity of per-and polyfluoroalkyl substances (PFAS)

V Ehrlich, W Bil, R Vandebriel, B Granum, M Luijten… - Environmental …, 2023 - Springer
Background Per-and polyfluoroalkyl substances (PFAS) are of public health concern,
because of their ubiquitous and extremely persistent occurrence, and depending on their …

Risk to human health related to the presence of perfluoroalkyl substances in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluoroalkyl substances (PFAS s) in food. Based …

Immunotoxicity mechanisms of perfluorinated compounds PFOA and PFOS

L Liang, Y Pan, L Bin, Y Liu, W Huang, R Li, KP Lai - Chemosphere, 2022 - Elsevier
Perfluorinated and polyfluorinated compounds (PFASs) are a class of synthetic chemical
substances that are widely used in human production and life, such as fire-fighting foams …

[HTML][HTML] Evolution of evidence on PFOA and health following the assessments of the C8 Science Panel

K Steenland, T Fletcher, CR Stein, SM Bartell… - Environment …, 2020 - Elsevier
Abstract Background The C8 Science Panel was composed of three epidemiologists
charged with studying the possible health effects of PFOA in a highly exposed population in …

Perfluoroalkyl substances exposure and immunity, allergic response, infection, and asthma in children: review of epidemiologic studies

H von Holst, P Nayak, Z Dembek, S Buehler… - Heliyon, 2021 - cell.com
Background Increased exposure to perfluoroalkyl substances (PFAS) potentially affects
infant and childhood health through immunosuppression. Given rapidly evolving research …

[HTML][HTML] Legacy per-and polyfluoroalkyl substances (PFASs) and alternatives (short-chain analogues, F-53B, GenX and FC-98) in residential soils of China: Present …

J Li, J He, Z Niu, Y Zhang - Environment international, 2020 - Elsevier
With the worldwide regulation of perfluorooctanoic acid (PFOA) and perfluorooctane
sulfonate (PFOS), the alternatives (short chain analogues and emerging per-and …

The occurrence of PFAS in human placenta and their binding abilities to human serum albumin and organic anion transporter 4

Y Lu, L Meng, D Ma, H Cao, Y Liang, H Liu… - Environmental …, 2021 - Elsevier
Both legacy and emerging per-and polyfluoroalkyl substances (PFAS) have been found to
be threats to human health. In particular, fetuses are sensitive to xenobiotics and the …

[HTML][HTML] A systematic evidence map of chronic inflammation and immunosuppression related to per-and polyfluoroalkyl substance (PFAS) exposure

L Zhang, A Louie, G Rigutto, H Guo, Y Zhao, S Ahn… - Environmental …, 2023 - Elsevier
Background The ability to induce chronic inflammation and immunosuppression are two key
characteristics of carcinogens and important forms of immunotoxicity. The National …

[HTML][HTML] Systematic review and meta-analysis of epidemiologic data on vaccine response in relation to exposure to five principal perfluoroalkyl substances

L Crawford, SA Halperin, MW Dzierlenga… - Environment …, 2023 - Elsevier
Background Epidemiologic studies of serum per-and polyfluoroalkyl substances (PFAS) and
antibody response to vaccines have suggested an adverse association, but the consistency …