In mammals, torpor/hibernation is a state that is characterized by an active reduction in
metabolic rate followed by a progressive decrease in body temperature. Torpor was …

Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers
have to accomplish to assess the effects of different experimental conditions on biological …

The idea of synthetic torpor, an artificial state resembling the hypo-metabolic state of
torpor/hibernation, has recently gained significant scientific attention. Building on pioneering …

The Raphe Pallidus (RPa) is a brainstem nucleus containing sympathetic premotor neurons
that control thermogenesis and modulate cardiovascular function. It receives inputs from …

Introduction: Hyperphosphorylated Tau protein (PPTau) is the hallmark of tauopathic
neurodegeneration. During “synthetic torpor”(ST), a transient hypothermic state which can …

Background Preclinical studies suggest body temperature (Tb) and consequently brain
temperature has the potential to bidirectionally interact with tau pathology in Alzheimer's …

Torpor is a state used by several mammals to survive harsh winters and avoid predation,
characterized by a drastic reduction in metabolic rate followed by a decrease in body …

Abstract Neuronal Tau protein hyperphosphorylation (PPtau) is a hallmark of tauopathic
neurodegeneration. However, a reversible brain PPtau occurs in mammals during either …

The ability to induce a hypothermia resembling that of natural torpor would be greatly
beneficial in medical and non-medical fields. At present, two procedures based on central …

Abstract The operationalization of Machine Learning (ML) models into production
environments, a process known as Machine Learning Operations (MLOps), represents a …