Individuals may opt to follow a plant-based diet for a variety of reasons, such as religious
practices, health benefits or concerns for animal or environmental welfare. Such diets offer a …

The placenta is a highly metabolically active organ fulfilling the bioenergetic and
biosynthetic needs to support its own rapid growth and that of the fetus. Placental metabolic …

In order to mount an appropriate immune response to infection, the macrophage must alter
its metabolism by increasing aerobic glycolysis and concomitantly decreasing oxidative …

The present review aims to explore and discuss recent research relating to the lactate
response to resistance training and the potential mechanisms by which lactate may …

Whilst it is universally accepted that the energy support of the brain is glucose, the form in
which the glucose is taken up by neurones is the topic of intense debate. In the last few …

Ischemic tissues accumulate succinate, which is rapidly oxidized upon reperfusion, driving a
burst of mitochondrial reactive oxygen species (ROS) generation that triggers cell death. In …

Purpose Although the effects of cadmium (Cd) on the development of diabetes have been
extensively investigated, the relationship between Cd exposure and the severity of …

Ischemic stroke is a serious condition that results in high rates of illness and death.
Anaerobic glycolysis becomes the primary means of providing energy to the brain during …

Background: Elevated plasma lactate levels correlate with high mortality rate in acute
pulmonary embolism (PE) patients. We hypothesized that elevated lactate levels correlate …

Tissue ischemia results in intracellular pH (pH IN) acidification, and while metabolism is a
known driver of acidic pH IN, less is known about how acidic pH IN regulates metabolism …