Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

[HTML][HTML] Electrochemical response of surface-attached redox DNA governed by low activation energy electron transfer kinetics

Z Zheng, SH Kim, A Chovin, N Clement… - Chemical Science, 2023 - pubs.rsc.org
The mechanism responsible for electron transport within layers of redox DNA anchored to
electrodes has been extensively studied over the last twenty years, but remains …

Modifying the properties of organic molecules by conjugation with metal complexes: The case of peptide nucleic acids and of the intrinsically chiral thiahelicenes

S Cauteruccio, E Licandro, M Panigati… - Coordination Chemistry …, 2019 - Elsevier
Modification of the properties of organic molecules by means of conjugation with transition
metals to obtain organometallic systems with improved reactivity, spectroscopic, and …

Electrical potential-assisted DNA hybridization. How to mitigate electrostatics for surface DNA hybridization

J Tymoczko, W Schuhmann… - ACS applied materials & …, 2014 - ACS Publications
Surface-confined DNA hybridization reactions are sensitive to the number and identity of
DNA capture probes and experimental conditions such as the nature and the ionic strength …

A Ruthenocene–PNA Bioconjugate Synthesis, Characterization, Cytotoxicity, and AAS-Detected Cellular Uptake

A Gross, N Hüsken, J Schur, Ł Raszeja… - Bioconjugate …, 2012 - ACS Publications
Labeling of peptide nucleic acids (PNA) with metallocene complexes is explored herein for
the modulation of the analytical characteristics, as well as biological properties of PNA. The …

[HTML][HTML] Enhancing Target Detection: A Fluorescence-Based Streptavidin-Bead Displacement Assay

S Tungsirisurp, N Frascione - Biosensors, 2024 - mdpi.com
Fluorescence-based aptasensors have been regarded as innovative analytical tools for the
detection and quantification of analytes in many fields, including medicine and therapeutics …

[HTML][HTML] Nucleic-acid recognition interfaces: how the greater ability of RNA duplexes to bend towards the surface influences electrochemical sensor performance

R Tavallaie, N Darwish, DB Hibbert… - Chemical …, 2015 - pubs.rsc.org
The influence of RNA versus DNA on the performance of electrochemical biosensors where
redox-labelled nucleic acid duplexes bend towards the electrode surface has been …

Rational design of a mismatched aptamer-DNA duplex probe to improve the analytical performance of electrochemical aptamer sensors

Z Zhang, C Tao - Electrochimica Acta, 2016 - Elsevier
Electrochemical aptamer sensors using electrode-bound, redox reporter-tagged aptamer
probes represent a unique biosensor platform for the selective and reagentless analysis of …

Preparation of a new electrochemical biosensor for single base mismatch detection in DNA

N Moradi, MF Mousavi, MA Mehrgardi, A Noori - Analytical Methods, 2013 - pubs.rsc.org
In this study, a sandwich-type electrochemical DNA hybridization biosensor for the detection
of single base mismatches (SBMs) has been described. 2, 5-Dihydroxybenzoic acid (DHBA) …

The electrochemical response of electrode-attached redox oligo-nucleotides is governed by low activation energy electron transfer kinetics

C Demaille, N Clément, A Chovin, SH Kim, Z Zheng - 2022 - chemrxiv.org
The mechanism responsible for electron transport within layers of redox DNA anchored to
electrodes has been the subject of numerous studies over the last twenty years, but remains …