Hyaluronan is a straight chain, glycosaminoglycan polymer of the extracellular matrix
composed of repeating units of the disaccharide [-d-glucuronic acid-β1, 3-N-acetyl-d …

[0003] Recently, ageneenCOdingthefu11-1engthDel-1has been cloned. Itis presumedthat
thefu11-1ength Del-1is CaPableofbinding, ViaapartOrtheentirereglOnthereof, tO …

The biosynthetic response of calf articular cartilage explants to dynamic compression was
examined over a wide range of amplitudes, waveforms, and frequencies …

The ability of chondrocytes from calf articular cartilage to synthesize and assemble a
mechanically functional cartilage‐like extracellular matrix was quantified in high cell density …

Initial assembly of extracellular matrix occurs within a zone immediately adjacent to the
chondrocyte cell surface termed the cell-associated or pericellular matrix. Assembly within …

General composition and structure Proteoglycans are macromolecules which consist of a
protein backbone to which GAG chain (s) and N-and/or 0-linked oligosaccharides are …

This study tested the effects of fluid‐induced shear on high density monolayer cultures of
adult articular chondrocytes. Fluid‐induced shear (1.6 Pa) was applied by cone viscometer …

Monoclonal antibodies were raised against proteoglycan core protein isolated after
chondroitinase ABC digestion of human articular cartilage proteoglycan monomer …

Sub-populations of bovine articular chondrocytes derived from different depths of the
cartilage showed differences in accumulation of proteoglycan-rich extracellular matrix in …

The composition of macroscopically normal hip articular cartilage obtained from dogs of
various ages was studied. Pieces of cartilage with signs of degeneration were studied …