Medial prefrontal cortex in neurological diseases

P Xu, A Chen, Y Li, X Xing, H Lu - Physiological genomics, 2019 - journals.physiology.org
The medial prefrontal cortex (mPFC) is a crucial cortical region that integrates information
from numerous cortical and subcortical areas and converges updated information to output …

Anxiety in synucleinopathies: neuronal circuitry, underlying pathomechanisms and current therapeutic strategies

TT Lai, B Gericke, M Feja, M Conoscenti… - npj Parkinson's …, 2023 - nature.com
Synucleinopathies are neurodegenerative disorders characterized by alpha-synuclein
(αSyn) accumulation in neurons or glial cells, including Parkinson's disease (PD), dementia …

Restoration and targeting of aberrant neurotransmitters in Parkinson's disease therapeutics

D Yadav, P Kumar - Neurochemistry international, 2022 - Elsevier
Neurotransmitters are considered as a fundamental regulator in the process of neuronal
growth, differentiation and survival. Parkinson's Disease (PD) occurs due to extensive …

Optimal treatment of depression and anxiety in Parkinson's disease

GM Pontone, KA Mills - The American journal of geriatric psychiatry, 2021 - Elsevier
Depression and anxiety are highly prevalent and have major adverse effects on function and
quality of life in Parkinson's disease (PD). Optimal management requires that motor …

[HTML][HTML] 5-HT7 receptors in Alzheimer's disease

M Solas, D Van Dam, J Janssens, U Ocariz… - Neurochemistry …, 2021 - Elsevier
Even though the involvement of serotonin (5-hydroxytryptamine; 5-HT) and its receptors in
Alzheimer's disease (AD) is widely accepted, data on the expression and the role of 5-HT 7 …

Altered small‐world functional network topology in patients with optic neuritis: A resting‐state fMRI study

K Song, J Li, Y Zhu, F Ren, L Cao… - Disease Markers, 2021 - Wiley Online Library
Aim. This study investigated changes in small‐world topology and brain functional
connectivity in patients with optic neuritis (ON) by resting‐state functional magnetic …

Neuropsychiatric disorders in Parkinson's disease: what do we know about the role of dopaminergic and non-dopaminergic systems?

K Dujardin, V Sgambato - Frontiers in neuroscience, 2020 - frontiersin.org
Besides the hallmark motor symptoms (rest tremor, hypokinesia, rigidity, and postural
instability), patients with Parkinson's disease (PD) have non-motor symptoms, namely …

[HTML][HTML] Anxiety in Parkinson's disease: correlation with depression and quality of life

A Upneja, BS Paul, D Jain… - … of neurosciences in …, 2021 - pmc.ncbi.nlm.nih.gov
Introduction Anxiety is common in patients with Parkinson's disease (PD). Its prevalence
ranges from 20 to 40% but despite that, the high prevalence anxiety in PD is often …

Report from a multidisciplinary meeting on anxiety as a non-motor manifestation of Parkinson's disease

GM Pontone, N Dissanayaka, L Apostolova… - npj Parkinson's …, 2019 - nature.com
Anxiety is a severe problem for at least one-third of people living with Parkinson's disease
(PD). Anxiety appears to have a greater adverse impact on quality of life than motor …

Recent advances in anxiety disorders: Focus on animal models and pathological mechanisms

H Zhao, M Zhou, Y Liu, J Jiang… - Animal Models and …, 2023 - Wiley Online Library
Anxiety disorders have become one of the most severe psychiatric disorders, and the
incidence is increasing every year. They impose an extraordinary personal and …