Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster
enzyme system in the body, which can effectively respond to cellular oxidative stress, lipid …

With the in-depth investigation of cardiac fibrosis, oxidative stress (OS) has been recognized
as a significant pathophysiological pathway inved in cardiac remodeling and progression …

Renal fibrosis is the common histopathological feature of chronic kidney diseases (CKD),
and there is increasing evidence that epigenetic regulation is involved in the occurrence and …

Significance: Physiological levels of reactive oxygen and nitrogen species (ROS/RNS)
function as fundamental messengers for many cellular and developmental processes in the …

Superoxide dismutase (SOD) can convert active oxygen to oxygen or hydrogen peroxide,
and recent research has suggested that it can protect against lung damage and fibrosis …

Epigenetic mechanisms and cell crosstalk have been shown to play important roles in the
initiation and progression of cardiac fibrosis. This review article aims to provide a thorough …

Genetic information is not transmitted solely by DNA but by the epigenetics process.
Epigenetics describes molecular missing link pathways that could bridge the gap between …

There is an increasing recognition of the crucial role of the right ventricle (RV) in determining
the functional status and prognosis in multiple conditions. In the past decade, the epigenetic …

Cardiac fibrosis is a common pathophysiologic process associated with numerous
cardiovascular diseases, resulting in cardiac dysfunction. Cardiac fibroblasts (CFs) play an …

This review will focus on epigenetic modifications utilizing the DNA methylation mechanism,
which is potentially involved in the pathogenesis of heart failure with preserved ejection …