Youthful and age‐related matreotypes predict drugs promoting longevity

C Statzer, E Jongsma, SX Liu, A Dakhovnik… - Aging …, 2021 - Wiley Online Library
The identification and validation of drugs that promote health during aging (“geroprotectors”)
are key to the retardation or prevention of chronic age‐related diseases. Here, we found that …

[HTML][HTML] Hsp90 facilitates acquired drug resistance of tumor cells through cholesterol modulation however independent of tumor progression

P Kumar, B Devaki, UK Jonnala… - Biochimica et Biophysica …, 2020 - Elsevier
Acquired multidrug resistance of cancer cells challenges the chemotherapeutic
interventions. To understand the role of molecular chaperone, Hsp90 in drug adapted tumor …

[HTML][HTML] Estudo das células Neuro2A sobre os biomateriais PCL e PLLA

LG Maturana, A Pierucci, GF Simões, ALR Oliveira… - Polímeros, 2014 - SciELO Brasil
Os biomateriais poli L-ácido lático (PLLA) e o poli caprolactona (PCL) são os polímeros
mais estudadas na área dos materiais bioreabsorvíveis. Dentre as suas principais …