Pathophysiology, prevention, and treatment of medication overuse headache

HC Diener, D Dodick, S Evers, D Holle… - The Lancet …, 2019 - thelancet.com
Regular or frequent use of analgesics and acute antimigraine drugs can increase the
frequency of headache, and induce the transition from episodic to chronic headache or …

Medication-overuse headache: a widely recognized entity amidst ongoing debate

N Vandenbussche, D Laterza, M Lisicki, J Lloyd… - The journal of headache …, 2018 - Springer
Medication overuse in primary headache disorders is a worldwide phenomenon and has a
role in the chronification of headache disorders. The burden of disease on individuals and …

Differential medication overuse risk of novel anti-migraine therapeutics

C Saengjaroentham, LC Strother, I Dripps… - Brain, 2020 - academic.oup.com
Medication overuse headache is estimated to affect 2% of the population, and is ranked in
the top 20 most disabling disorders due to its high level of disability. Several therapies used …

Medication-overuse headache

BR Wakerley - Practical neurology, 2019 - pn.bmj.com
Medication-overuse headache is defined as headache occurring on more than 15days in a
month in people with pre-existing primary headache, and developing as a consequence of …

Evaluation of LY573144 (lasmiditan) in a preclinical model of medication overuse headache

JC Rau, E Navratilova, J Oyarzo, KW Johnson… - …, 2020 - journals.sagepub.com
Background Medication overuse is a significant issue that complicates the treatment of
headache disorders. The most effective medications for the acute treatment of migraine all …

Medication-overuse headache

P Rizzoli - CONTINUUM: Lifelong Learning in Neurology, 2024 - journals.lww.com
Objective Medication-overuse headache (MOH) has been described for almost 100 years
and is characterized as a daily or near-daily headache that usually presents in patients with …

Genetic variants associated with response to anti-CGRP monoclonal antibody therapy in a chronic migraine Han Chinese population

YC An, KS Hung, CS Liang, CK Tsai, CL Tsai… - The Journal of …, 2024 - Springer
Background Anti-calcitonin gene-related peptide (CGRP) monoclonal antibodies have
emerged as promising therapeutic options for the treatment of chronic migraine. However …

Therapies targeting CGRP signaling for medication overuse headache

IA Koumprentziotis, DD Mitsikostas - Current Opinion in Neurology, 2022 - journals.lww.com
The available data indicate that anti-CGRP mAbs represent a good mechanism-based and
disease-specific therapeutical option with for MOH as long as detoxification and additional …

Personality and personality disorders in medication‐overuse headache: A controlled study by SWAP‐200

F Galli, A Tanzilli, A Simonelli… - Pain Research and …, 2019 - Wiley Online Library
Background. Medication‐overuse headache (MOH) is a type of chronic headache, whose
mechanisms are still unknown. The impact of psychological factors has been matter of …

Medication overuse headache

S Ashina, GM Terwindt, TJ Steiner, MJ Lee… - Nature Reviews …, 2023 - nature.com
Medication overuse headache (MOH) is a secondary headache disorder attributed to
overuse of acute headache medications by a person with an underlying headache disorder …