Examining the quaternary ammonium chitosan Schiff base-ZnO nanocomposite's potential as protective therapy for rats' cisplatin-induced hepatotoxicity

ES Kotb, HW Alhamdi, MY Alfaifi, O Darweesh… - International Journal of …, 2024 - Elsevier
Background Despite cisplatin's long history as a cornerstone in cancer therapy, both
acquired chemoresistance and significant impacts on healthy tissues limit its use …

Au/SiNCA-based SERS analysis coupled with machine learning for the early-stage diagnosis of cisplatin-induced liver injury

S Ge, G Chen, D Cao, H Lin, Z Liu, M Yu, S Wang… - Analytica Chimica …, 2023 - Elsevier
Cisplatin has been widely applied in the clinical treatment of various cancers, whereas liver
injury induced by its hepatotoxicity is still a severe issue. Reliable identification of early …

Antioxidant Role of Beta-glucan on Cisplatin-induced Liver Injury in Rats

BD Yılmaz - Northern Journal of Health Sciences, 2025 - dergipark.org.tr
Objective: Cisplatin (cisdiamminedichloridoplatinum II [CDDP]) is an antineoplastic cancer
drug frequently used in the treatment of a wide variety of cancers. In addition to its positive …

Biochemical and histological investigation of azathioprine and melatonin in rats

AΑ Hussein, MΗ Ahmed… - Journal of the …, 2024 - ejournals.epublishing.ekt.gr
Azathioprine (AZA) is a purine antagonist, also known as Imuran or Azapress, is a commonly
prescribed immunosuppressive drug that is used in the management of many conditions …

Research on Endoplasmic Reticulum Stress-mediated Protective Effect of Melatonin against Cardiotoxicity Following Cisplatin Treatment

T Ceylan, M Ünsal, E Kaymak, AT Akin, N Kuloğlu… - 2024 - acikerisim.kapadokya.edu.tr
Objective: Cisplatin (CP) is a chemotherapeutic drug that causes cardiotoxicity. Melatonin
(MEL) is secreted by the pineal gland throughout the night. This study aimed to investigate …

Histological Evaluation of the Protective Role of β-glucan Against Cisplatin-Induced Hepatotoxicity

BD Yılmaz, B Eren, D Sağır, A Başardı… - … Mühendislik ve Doğa … - dergipark.org.tr
Sisplatin pek çok kanserin tedavisinde sıklıkla kullanılan kemoterapötik bir ajandır. En
önemli doz sınırlayıcı yan etkisi hepatotoksisitedir. Bu çalışmada, sisplatin tedavisinin …