Simple Summary Medical control of cancer pain is often unsatisfactory. Narcotic drugs
(opioids) are effective pain killers, but they have important negative effects on the central …

Polysulfides are endogenously produced in mammals and generally associated with
protective functions. Our aim was to investigate the effect of dimethyl trisulfide (DMTS) in a …

Fibromyalgia (FM) is a complex and multifaceted condition characterized by a range of
clinical symptoms, including widespread pain and a strong association with migraine …

Background and Purpose Fibromyalgia is a complex clinical disorder with an unknown
aetiology, characterized by generalized pain and co‐morbid symptoms such as anxiety and …

Ultrasound is highly biopermeable and can non-invasively penetrate deep into the brain.
Stimulation with patterned low-intensity ultrasound can induce sustained inhibition of neural …

Objective Transgenic mice with fluorescent protein (FP) reporters take full advantage of new
in vivo imaging technologies. Therefore, we generated a TRPC5-and a TRPA1-reporter …

The TRPA1 ion channel is a sensitive detector of reactive chemicals, found primarily on
sensory neurons. The phenotype exhibited by mice lacking TRPA1 suggests its potential as …

While the eye's surface is constantly exposed to microbes in the environment, healthy
corneas lack a microbiome and have an unusual ability to resist colonization and infection …