Checkpoint inhibitor immune therapy: systemic indications and ophthalmic side effects

LA Dalvin, CL Shields, M Orloff, T Sato, JA Shields - Retina, 2018 - journals.lww.com
Purpose: To review immune checkpoint inhibitor indications and ophthalmic side effects.
Methods: A literature review was performed using a PubMed search for publications …

[HTML][HTML] Myasthenia gravis: an emerging toxicity of immune checkpoint inhibitors

D Makarious, K Horwood, JIG Coward - European Journal of Cancer, 2017 - Elsevier
The advent of immunotherapy has heralded a number of significant advances in the
treatment of particular malignancies associated with poor prognosis (melanoma, non-small …

Immune checkpoint inhibitor-related myositis and myocarditis in patients with cancer

M Touat, T Maisonobe, S Knauss, O Ben Hadj Salem… - Neurology, 2018 - AAN Enterprises
Objective To report the clinicopathologic features and outcome of myositis in patients treated
with immune checkpoint inhibitors (ICIs)(irMyositis). Methods We retrospectively analyzed …

Neurological toxicities associated with immune-checkpoint inhibitors

M Touat, D Talmasov, D Ricard… - Current opinion in …, 2017 - journals.lww.com
ICI-associated irAEs constitute a new group of neurologic complications of systemic
anticancer therapies. Although potentially severe, these rare neurologic toxicities are often …

Neuromuscular adverse events associated with anti-PD-1 monoclonal antibodies: systematic review

A Johansen, SJ Christensen, D Scheie, JLS Højgaard… - Neurology, 2019 - AAN Enterprises
Neuromuscular adverse events following cancer treatment with anti-programmed cell death
protein 1 (PD-1) monoclonal antibodies are relatively rare, yet potentially fatal. We …

[HTML][HTML] Immune checkpoint inhibitor-induced myasthenia gravis

YT Huang, YP Chen, WC Lin, WC Su, YT Sun - Frontiers in neurology, 2020 - frontiersin.org
The development of immune checkpoint inhibitors (ICIs) has been a major breakthrough in
cancer immunotherapy. The increasing use of ICIs has led to the discovery of a broad …

[HTML][HTML] Immune checkpoint inhibitor-associated cardiotoxicity: current understanding on its mechanism, diagnosis and management

YW Zhou, YJ Zhu, MN Wang, Y Xie, CY Chen… - Frontiers in …, 2019 - frontiersin.org
Immune checkpoint inhibitors (ICIs) that target cytotoxic T lymphocyte antigen 4,
programmed cell death-1, and PD-ligand 1 have revolutionized cancer treatment, achieving …

Neuromuscular complications of programmed cell death-1 (PD-1) inhibitors

JC Kao, A Brickshawana, T Liewluck - Current Neurology and …, 2018 - Springer
Abstract Purpose of Review In recent years, immune checkpoint inhibitors have been
increasingly used in patients with metastatic cancers with favorable oncological outcomes; …

[HTML][HTML] Safety and tolerability of immune checkpoint inhibitors (PD-1 and PD-L1) in cancer

I Baraibar, I Melero, M Ponz-Sarvise, E Castanon - Drug safety, 2019 - Springer
Immunotherapy has emerged in recent years and has revolutionized the treatment of cancer.
Immune checkpoint inhibitors, including anti-cytotoxic T lymphocyte antigen-4 (CTLA-4), anti …

Neurological adverse events associated with immune checkpoint inhibitors: diagnosis and management

C Astaras, R de Micheli, B Moura… - Current Neurology and …, 2018 - Springer
Abstract Purpose of Review Immune checkpoint inhibitors represent a major step forward in
the field of oncologic immunotherapy these last years and have significantly increased …