Chemistry and bioactivity of lindenane sesquiterpenoids and their oligomers

J Luo, D Zhang, P Tang, N Wang, S Zhao… - Natural Product …, 2024 - pubs.rsc.org
Covering: 1925 to July 2023 Among the sesquiterpenoids with rich structural diversity and
potential bioactivities, lindenane sesquiterpenoids (LSs) possess a characteristic cis, trans …

Naturally occurring [4+ 2] type terpenoid dimers: sources, bioactivities and total syntheses

B Liu, S Fu, C Zhou - Natural Product Reports, 2020 - pubs.rsc.org
Covering: up to January 2020 [4+ 2] type terpenoid dimers are natural products
biosynthetically derived from [4+ 2] cycloaddition between two terpenoid monomers. They …

Spirolindemers A and B, Lindenane Sesquiterpenoid Oligomers Equipped with Oxaspiro[4.5]decane from Chloranthus henryi

J Li, J Chi, P Tang, Y Sun, W Lu, W Xu… - Chinese Journal of …, 2022 - Wiley Online Library
Comprehensive Summary Spirolindemers A and B, unprecedented lindenane
sesquiterpenoid dimer (1) and trimer (2) equipped with oxaspiro [4.5] decane unit, were …

Natural and Pseudonatural Lindenane Heterodimers from Sarcandra glabra by Molecular Networking

Z Cui, Y Wang, J Li, J Chi, P Zhang, L Kong… - Organic Letters, 2022 - ACS Publications
Sarglaoxolane A (1), the first lindenane–normonoterpene heterodimer fused by
tetrahydrofuran, was discovered in Sarcandra glabra guided by the first proposed single …

Picomolar antimalarial agent from a Chinese medicinal plant

B Zhou, FM Zimbres, JH Butler, CH Xu… - Science China …, 2022 - Springer
In our long-term efforts searching for antimalarial agents from Chinese medicinal plants,
seven novel dimeric sesquiterpenoids (1–7) with significant antimalarial activity were …

Trichloranoids A–D, antimalarial sesquiterpenoid trimers from Chloranthus spicatus

JS Zhou, QF Liu, FM Zimbres, JH Butler… - Organic Chemistry …, 2021 - pubs.rsc.org
Four new lindenane sesquiterpenoid trimers, designated as trichloranoids A–D (1–4), along
with a known analogue (5) were isolated from Chloranthus spicatus. Their structures were …

Natural disesquiterpenoids: an update

LF Ma, YL Chen, WG Shan, ZJ Zhan - Natural Product Reports, 2020 - pubs.rsc.org
Covering: July 2010 to August 2019. Previous review: Nat. Prod. Rep., 2011, 28, 594 The
review covers recent progress on the isolation, identification, bioactivity and biomimetic …

Chlotrichenes A and B, Two Lindenane Sesquiterpene Dimers with Highly Fused Carbon Skeletons from Chloranthus holostegius

J Chi, W Xu, S Wei, X Wang, J Li, H Gao, L Kong… - Organic …, 2019 - ACS Publications
Two unprecedented lindenane sesquiterpene dimers, chlotrichenes A (1) and B (2), were
obtained from Chloranthus holostegius var. trichoneurus. Their structures were …

Chlospicenes A and B, cyclopropane cracked lindenane sesquiterpenoid dimers with anti-nonalcoholic steatohepatitis activity from Chloranthus henryi

J Li, Z Cui, Y Li, C Han, Y Zhang, P Tang, L Cui… - Chinese Chemical …, 2022 - Elsevier
Guided by MS/MS molecular networks strategy, chlospicenes A and B (1 and 2), the first
example of cyclopropane moiety cracked lindenane sesquiterpene Michael addition dimers …

Asymmetric Total Synthesis of Shizukaol J, Trichloranoid C and Trishizukaol A

X Wang, Z Wang, X Ma, Z Huang, K Sun… - Angewandte …, 2022 - Wiley Online Library
The asymmetric total synthesis of three lindenane sesquiterpenoid oligomers, shizukaol J,
trichloranoid C and trishizukaol A, has been accomplished concisely in 15, 16 and 18 …