Nanoparticle‐Based Photothermal Therapy for Breast Cancer Noninvasive Treatment

Y Xiong, Y Rao, J Hu, Z Luo, C Chen - Advanced materials, 2023 - Wiley Online Library
Rapid advancements in materials science and nanotechnology, intertwined with oncology,
have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy …

The role of TRAIL in apoptosis and immunosurveillance in cancer

JM Pimentel, JY Zhou, GS Wu - Cancers, 2023 - mdpi.com
Simple Summary Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)
plays an important role in apoptosis and tumor immunosurveillance. Because TRAIL …

Enhanced anticancer efficacy of TRAIL-conjugated and odanacatib-loaded PLGA nanoparticles in TRAIL resistant cancer

TTK Nguyen, SM Woo, SU Seo, A Banstola, H Kim… - Biomaterials, 2025 - Elsevier
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) demonstrates unique
characteristics in anticancer therapies as it selectively induces apoptosis in cancer cells …

From interaction to intervention: how mesenchymal stem cells affect and target triple-negative breast cancer

Y Wu, HCE Shum, K Wu, J Vadgama - Biomedicines, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) lacks estrogen receptor, progesterone receptor, and
human epidermal growth factor receptor 2 expressions, making targeted therapies …

Engineered extracellular vesicles with DR5 agonistic scFvs simultaneously target tumor and immunosuppressive stromal cells

Y Guo, H Wang, S Liu, X Zhang, X Zhu, L Huang… - Science …, 2025 - science.org
Small extracellular vesicles (sEVs) are nanosized vesicles. Death receptor 5 (DR5)
mediates extrinsic apoptosis. We engineer DR5 agonistic single-chain variable fragment …

Cytoplasmic TP53INP2 acts as an apoptosis partner in TRAIL treatment: the synergistic effect of TRAIL with venetoclax in TP53INP2-positive acute myeloid leukemia

J Ren, J Huang, Z Yang, M Sun, J Yang, C Lin… - Journal of Experimental …, 2024 - Springer
Background Acute myeloid leukemia (AML) is a hematopoietic malignancy with poor
outcomes, especially in older AML patients. Tumor necrosis factor-related apoptosis …

Exploring hypoxia-induced ncRNAs as biomarkers and therapeutic targets in lung cancer

L Thangavelu, M Imran, SH Alsharari… - … -Research and Practice, 2024 - Elsevier
Lung cancer is a deadly disease, causing nearly 20% of all cancer deaths globally. A key
factor in lung cancer's development and resistance to treatment is hypoxia, a condition …

Combination treatment of bortezomib and epirubicin increases the expression of TNFRSF10 A/B, and induces TRAIL-mediated cell death in colorectal cancer cells

F Caldiran, C Berkel, E Yilmaz, B Kucuk… - Biochemical and …, 2023 - Elsevier
Colorectal cancer is one of the most common cancers worldwide, affecting the colon and
rectum. A major problem in the treatment of colorectal cancer is acquired chemoresistance …

[HTML][HTML] The Role of Osteoprotegerin in Breast Cancer: Genetic Variations, Tumorigenic Pathways, and Therapeutic Potential

JH Radhi, AMA El-Hagrasy, SH Almosawi, A Alhashel… - Cancers, 2025 - mdpi.com
Abstract Introduction: Osteoprotegerin (OPG), encoded by the TNFRSF11B gene, is linked to
the development of breast cancer via several pathways, including interactions with the …

Ashwagandha-Induced Programmed Cell Death in the Treatment of Breast Cancer

R Kołodziejska, A Tafelska-Kaczmarek… - Current Issues in …, 2024 - pmc.ncbi.nlm.nih.gov
The aim of this review is to provide experimental evidence for the programmed-death activity
of Ashwagandha (Withania somnifera) in the anti-cancer therapy of breast cancer. The …