The irritable bowel syndrome (IBS) is part of the larger group of functional gastrointestinal
(GI) disorders that, despite differences in location and symptom patterns, share common …

Over the past two centuries, prevalent models of energy and glucose homeostasis have
emerged from careful anatomical descriptions in tandem with an understanding of cellular …

This review highlights evidence for a role of the vagus nerve in the development of obesity
and how targeting the vagus nerve with neuromodulation or pharmacology can be used as a …

▪ Abstract Brainstem parasympathetic circuits that modulate digestive functions of the
stomach are comprised of afferent vagal fibers, neurons of the nucleus tractus solitarius …

The physiological control of appetite regulation involves circulating hormones with
orexigenic (appetite-stimulating) and anorexigenic (appetite-inhibiting) properties that …

Neurohumoral substances and their receptors play a major part in the complex regulation of
gastrointestinal motility and have therefore been the predominant targets for drug …

Gastrointestinal (GI) vagal afferents convey sensory signals from the GI tract to the brain.
Numerous subtypes of GI vagal afferent have been identified but their individual roles in gut …

BACKGROUND: This article outlines our current perioperative management of patients
undergoing cystectomy and urinary diversion using advancements in perioperative care to …

The irritable bowel syndrome (IBS) is a common chronic functional gastrointestinal disorder
world wide that lasts for decades. The human gut harbors a diverse population of microbial …

The gastrointestinal tract has its own “brain,” the enteric nervous system or ENS, that
executes routine housekeeping functions of digestion. The dorsal vagal complex in the …