Investigation of toll-like receptor (TLR) 4 inhibitor TAK-242 as a new potential anti-rheumatoid arthritis drug
Background Proper blocking of toll-like receptor (TLR) activation during disease progression
has been reported to have inhibitory effect on the pathogenesis of rheumatoid arthritis (RA) …
has been reported to have inhibitory effect on the pathogenesis of rheumatoid arthritis (RA) …
Interleukin 17 regulates SHP-2 and IL-17RA/STAT-3 dependent Cyr61, IL-23 and GM-CSF expression and RANKL mediated osteoclastogenesis by fibroblast-like …
Abstract Interleukin (IL)-17 predominately produced by the Th17 cells, plays a crucial role in
the fibroblast-like synoviocytes (FLS) mediated disease process of rheumatoid arthritis (RA) …
the fibroblast-like synoviocytes (FLS) mediated disease process of rheumatoid arthritis (RA) …
Pathophysiology, diagnosis, and herbal medicine-based therapeutic implication of rheumatoid arthritis: an overview
Rheumatoid arthritis (RA) stands as an autoimmune disorder characterized by chronic joint
inflammation, resulting in profound physiological alterations within the body. Affecting …
inflammation, resulting in profound physiological alterations within the body. Affecting …
PdCl2-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl/aminocarboxamide moiety: First identification of a isocoumarin based …
While anti-inflammatory properties of isocoumarins are known their PDE4 inhibitory potential
was not explored previously. In our effort the non-PDE4 inhibitor isocoumarins were …
was not explored previously. In our effort the non-PDE4 inhibitor isocoumarins were …
Role of folate-conjugated glycol-chitosan nanoparticles in modulating the activated macrophages to ameliorate inflammatory arthritis: in vitro and in vivo activities
Activated macrophages are the primary targets in rheumatoid arthritis (RA) management.
So, we report efficacious, dual-functional Methotrexate (MTX) loaded folate-conjugated pH …
So, we report efficacious, dual-functional Methotrexate (MTX) loaded folate-conjugated pH …
[HTML][HTML] α-linolenic acid inhibits receptor activator of NF-κB ligand induced (RANKL-induced) Osteoclastogenesis and prevents inflammatory bone loss via …
J Song, Z Jing, W Hu, J Yu, X Cui - Medical Science Monitor …, 2017 - ncbi.nlm.nih.gov
Background Inflammation is a major cellular strain causing increased risk of osteo-
degenerative diseases. Omega-3 fatty acids have been great source in suppressing …
degenerative diseases. Omega-3 fatty acids have been great source in suppressing …
Interleukin 17 under hypoxia mimetic condition augments osteoclast mediated bone erosion and expression of HIF-1α and MMP-9
Abstract Interleukin 17 (IL-17) and hypoxia have been implicated to play a key role in
rheumatoid arthritis (RA). In this study, the combined treatment of IL-17 and cobalt chloride …
rheumatoid arthritis (RA). In this study, the combined treatment of IL-17 and cobalt chloride …
Ferulic acid inhibits interleukin 17‐dependent expression of nodal pathogenic mediators in fibroblast‐like synoviocytes of rheumatoid arthritis
Abstract Interleukin 17 (IL‐17), a proinflammatory cytokine produced by T helper (Th) 17
cells, potentially controls fibroblast‐like synoviocytes (FLS)‐mediated disease activity of …
cells, potentially controls fibroblast‐like synoviocytes (FLS)‐mediated disease activity of …
Extraction, phytochemical characterization and anti-cancer mechanism of Haritaki churna: An ayurvedic formulation
MRUZ Khan, E Yanase, V Trivedi - Plos one, 2023 - journals.plos.org
Haritaki churna (HC), a single herb ayurvedic formulations is known to be prescribed for
various gastro-intestinal disorders in Ayurveda. Haritaki churna aqueous extract (HCAE) has …
various gastro-intestinal disorders in Ayurveda. Haritaki churna aqueous extract (HCAE) has …
[HTML][HTML] The continuing problem of poor transparency of reporting and use of inappropriate methods for RT-qPCR
S Bustin - Biomolecular Detection and Quantification, 2017 - Elsevier
The continuing problem of poor transparency of reporting and use of inappropriate methods for
RT-qPCR - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …
RT-qPCR - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …