Declining female fertility has become a global health concern. It results partially from an
abnormal circadian clock caused by unhealthy diet and sleep habits in modern life. The …

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The circadian rhythm, which is necessary for reproduction, is controlled by clock genes. In
the mouse uterus, the oscillation of the circadian clock gene has been observed. The …

Men and women exhibit notable differences not only in the reproductive system and
reproductive behaviors, but in many other organ and physiological systems as well. Notable …

Male infertility is a global health problem that disturbs numerous couples worldwide.
Basonuclin 1 (BNC1) is a transcription factor mainly expressed in proliferative keratinocytes …

Shiftwork, including work that takes place at night (nightshift) and/or rotates between day
and nightshifts, plays an important role in our society, but is associated with decreased …

Background Exposure to the ionizing radiation (IR) encountered outside the magnetic field
of the Earth poses a persistent threat to the reproductive functions of astronauts. The …

For billions of years before electric light was invented, life on Earth evolved under the pattern
of light during the day and darkness during the night. Through evolution, nearly all …

Obesity impacts fertility and is positively correlated with endometrial hyperplasia and
endometrial cancer occurrence. Endometrial epithelia often harbor disease driver-mutations …

MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression
at the post-transcriptional level and play critical roles in regulating physiological function …