Inhibitory activities of indolizine derivatives: a patent review
Introduction Indolizines are structural isomers with indoles. Although several indole-based
commercial drugs are available in the market, none of the indolizine-based drugs are …
commercial drugs are available in the market, none of the indolizine-based drugs are …
Design, synthesis, characterization, and anti-tubercular activity of novel ethyl-3-benzoyl-6, 8-difluoroindolizine-1-carboxylate analogues: Molecular target identification …
P Mundhe, S Kidwai, SM Saini, HR Singh… - Journal of Molecular …, 2023 - Elsevier
A series of novel Ethyl-3-benzoyl-6, 8-difluoroindolizine-1-carboxylate analogues (4a-r)
were synthesized by reacting 3, 5-difluoropyridine, with phenacyl bromide to get quaternary …
were synthesized by reacting 3, 5-difluoropyridine, with phenacyl bromide to get quaternary …
A Review on the Synthesis of Fluorescent Five-and Six-Membered Ring Azaheterocycles
Azaheterocycles rings with five and six members are important tools for the obtaining of
fluorescent materials and fluorescent sensors. The relevant advances in the synthesis of …
fluorescent materials and fluorescent sensors. The relevant advances in the synthesis of …
Investigation of antifungal properties of synthetic dimethyl-4-bromo-1-(substituted benzoyl) pyrrolo [1, 2-a] quinoline-2, 3-dicarboxylates analogues: Molecular docking …
V Uppar, S Chandrashekharappa, C Shivamallu, SP… - Molecules, 2021 - mdpi.com
Candida albicans, an opportunistic fungal pathogen, frequently colonizes immune-
compromised patients and causes mild to severe systemic reactions. Only few antifungal …
compromised patients and causes mild to severe systemic reactions. Only few antifungal …
Tandem-Michael-cyclization cascade to make pyridines: Use of electron-deficient acetylenes for the synthesis of indolizines in aqueous media
K Lakshmikanth, SM Saini, ST Dorai… - Tetrahedron, 2023 - Elsevier
A mild, greener approach via tandem-Michael-cyclization cascade reaction towards the
construction of a group of di-and tri-differently substituted indolizine with a broad scope of …
construction of a group of di-and tri-differently substituted indolizine with a broad scope of …
Synthesis of novel pyrrolo [1, 2-a] quinoline derivatives as a new class of anti-inflammatory and antimicrobial agents: An approach to single crystal X-ray structure …
We report the synthesis and characterisation of pyrrolo [1, 2-a] quinoline derivatives 3a-c.
The synthesised compounds were characterised by FTIR, 1 H NMR, 13 C NMR, and mass …
The synthesised compounds were characterised by FTIR, 1 H NMR, 13 C NMR, and mass …
Anti-tubercular activity of substituted 7-methyl and 7-formylindolizines and in silico study for prospective molecular target identification
Novel series of diversely substituted indolizines were designed, synthesized, and evaluated
for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) …
for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) …
Microwave-assisted improved regioselective synthesis of 3-benzoyl indolizine derivatives
An efficient and facile method is developed to synthesize 3-benzoyl indolizines by two-
component reaction under microwave irradiation. A wide range of substrates could be …
component reaction under microwave irradiation. A wide range of substrates could be …
Synthesis and characterization of pyrrolo[1,2-a]quinoline derivatives for their larvicidal activity against Anopheles arabiensis
V Uppar, S Chandrashekharappa, KN Venugopala… - Structural Chemistry, 2020 - Springer
Abstract Certain tetrahydropyrido [1, 2-a] quinolines and pyrroloquinoline homologs have
shown various biological activities such as antimicrobials, crop-protectings, diuretics …
shown various biological activities such as antimicrobials, crop-protectings, diuretics …
Molecular modeling studies and anti-TB activity of trisubstituted indolizine analogues; molecular docking and dynamic inputs
MA Khedr, M Pillay… - Journal of …, 2018 - Taylor & Francis
A series of trisubstituted indolizine analogues has been designed as a result of a fragment-
based approach to target the inhibition of mycobacterial enoyl-acyl carrier protein reductase …
based approach to target the inhibition of mycobacterial enoyl-acyl carrier protein reductase …