The β2-integrin receptor family has a broad spectrum of physiological functions ranging from
leukocyte adhesion, cell migration, activation, and communication to the phagocytic uptake …

Important insights into leukocyte differentiation and the cellular origins of leukemia and
lymphoma have been gained through the use of monoclonal antibodies that define cell …

Identity of the Epstein-Barr virus (EBV) receptor with the complement receptor type 2 (CR2)
was established in three sets of experiments using the monoclonal antibodies, HB-5 and …

Apoptotic cells are rapidly engulfed by phagocytes, but the receptors and ligands
responsible for this phenomenon are incompletely characterized. Previously described …

We have determined the high resolution crystal structure of the A domain from the a chain of
integrin CR3. The domain adopts a classic α/β “Rossmann” fold and contains an unusual …

Integrin α M β 2 (Mac-1, CD11b/CD18) is a noncovalently linked heterodimer of α M and β 2
subunits on the surface of leukocytes, where it plays a pivotal role in the adhesion and …

To learn if refractory periodontitis may be associated with defects in peripheral blood
polymorphonuclear leukocyte (PMN) function, phagocytosis and chemotaxis were analyzed …

Helicobacter pylori-associated gastritis is mainly an inflammatory cell response. In earlier
work we showed that activation of human neutrophils by a cell-free water extract of H. pylori …

A monoclonal antibody (904) that binds to a leukocyte cell adhesion-promoting
glycoprotein,(Mo1; CD11b/CD18) was administered (1 mg/kg, iv.) to open chest …

A purified recombinant human granulocyte-macrophage colony stimulating factor (rH GM-
CSF) was a powerful stimulator of mature human eosinophils and neutrophils. The purified …