Data and theory point to mainly additive genetic variance for complex traits

WG Hill, ME Goddard, PM Visscher - PLoS genetics, 2008 - journals.plos.org
The relative proportion of additive and non-additive variation for complex traits is important
in evolutionary biology, medicine, and agriculture. We address a long-standing controversy …

Twin studies as a model for exploring the aetiology of autoimmune thyroid disease

TH Brix, L Hegedüs - Clinical endocrinology, 2012 - Wiley Online Library
Twins are an important resource for evaluating the relative contribution of genetic and
environmental factors in determining a phenotype. During the last decades, a number of twin …

Childhood attention‐deficit hyperactivity disorder as an extreme of a continuous trait: A quantitative genetic study of 8,500 twin pairs

H Larsson, H Anckarsater, M Råstam… - Journal of Child …, 2012 - Wiley Online Library
Background: Although the clinical utility of categorically defined attention‐deficit
hyperactivity disorder (ADHD) is well established, there is also strong evidence supporting …

Genetics, personality and wellbeing. A twin study of traits, facets and life satisfaction

E Røysamb, RB Nes, NO Czajkowski, O Vassend - Scientific reports, 2018 - nature.com
Human wellbeing is influenced by personality traits, in particular neuroticism and
extraversion. Little is known about which facets that drive these associations, and the role of …

A developmental twin study of symptoms of anxiety and depression: evidence for genetic innovation and attenuation

KS Kendler, CO Gardner, P Lichtenstein - Psychological medicine, 2008 - cambridge.org
BackgroundLittle is known about the pattern of genetic and environmental influences on
symptoms of anxiety and depression (SxAnxDep) from childhood to early adulthood …

Dimensional representations of DSM-IV cluster B personality disorders in a population-based sample of Norwegian twins: a multivariate study

S Torgersen, N Czajkowski, K Jacobson… - Psychological …, 2008 - cambridge.org
BackgroundThe personality disorders (PDs) in the 'dramatic'cluster B [antisocial (ASPD),
histrionic (HPD), narcissistic (NPD) and borderline (BPD)] demonstrate co-morbidity …

A population-based heritability estimate of bipolar disorder–In a Swedish twin sample

V Johansson, R Kuja-Halkola, TD Cannon… - Psychiatry …, 2019 - Elsevier
Twin-and family studies have shown variations in the heritability estimates of bipolar
disorder (BPD). The current study uses an updated statistical methodology for heritability …

A power calculator for the classical twin design

B Verhulst - Behavior genetics, 2017 - Springer
Power is a ubiquitous, though often overlooked, component of any statistical analyses.
Almost every funding agency and institutional review board requires that some sort of power …

The etiology of variation in language skills changes with development: A longitudinal twin study of language from 2 to 12 years

ME Hayiou‐Thomas, PS Dale… - Developmental …, 2012 - Wiley Online Library
The present study is the first long‐term longitudinal examination of the etiology of individual
differences in language from early childhood through to adolescence. We applied a …

Correlations between social dominance orientation and political attitudes reflect common genetic underpinnings

TH Kleppestø, NO Czajkowski… - Proceedings of the …, 2019 - National Acad Sciences
A foundational question in the social sciences concerns the interplay of underlying causes in
the formation of people's political beliefs and prejudices. What role, if any, do genes …