Common themes in zoonotic spillover and disease emergence: Lessons learned from bat-and rodent-borne RNA viruses

EP Williams, BM Spruill-Harrell, MK Taylor, J Lee… - Viruses, 2021 - mdpi.com
Rodents (order Rodentia), followed by bats (order Chiroptera), comprise the largest
percentage of living mammals on earth. Thus, it is not surprising that these two orders …

Vaccine candidates against arenavirus infections

T Saito, RA Reyna, S Taniguchi, K Littlefield… - Vaccines, 2023 - mdpi.com
The viral family Arenaviridae contains several members that cause severe, and often lethal,
diseases in humans. Several highly pathogenic arenaviruses are classified as Risk Group 4 …

NRP2 and CD63 are host factors for Lujo virus cell entry

M Raaben, LT Jae, AS Herbert, AI Kuehne, SH Stubbs… - Cell host & …, 2017 - cell.com
Arenaviruses cause fatal hemorrhagic disease in humans. Old World arenavirus
glycoproteins (GPs) mainly engage α-dystroglycan as a cell-surface receptor, while New …

Recent developments on Junin virus, a causative agent for Argentine haemorrhagic fever

S Kumar, D Yadav, D Singh, K Shakya… - Reviews in Medical …, 2023 - Wiley Online Library
Junin virus consists of ribonucleic acid as the genome and is responsible for a rapidly
changing tendency of the virus. The virus is accountable for ailments in the human body and …

Unveiling the hidden threats: a review of pathogen diversity and public health risks from bats, rodents, and non-human primates in Zambia (1990–2022)

SM Munjita, B Mubemba, K Changula… - Frontiers in Public …, 2024 - frontiersin.org
Background Infectious disease agents of animal origin, which can cause mild to severe
illnesses in humans, are increasingly spilling over into human populations. Southern Africa …

[HTML][HTML] Strategies of rational and structure-driven vaccine design for Arenaviruses

AS Peter, DS Hoffmann, J Klier, CM Lange… - Infection, Genetics and …, 2024 - Elsevier
The COVID-19 outbreak has highlighted the importance of pandemic preparedness for the
prevention of future health crises. One virus family with high pandemic potential are …

Recent advances in the development and evaluation of molecular diagnostics for Ebola virus disease

J Tembo, E Simulundu, K Changula… - Expert Review of …, 2019 - Taylor & Francis
ABSTRACT Introduction: The 2014-16 outbreak of ebola virus disease (EVD) in West Africa
resulted in 11,308 deaths. During the outbreak only 60% of patients were laboratory …

Immunoinformatic based designing of highly immunogenic multi-epitope subunit vaccines to stimulate an adaptive immune response against Junin virus

M Alissa, A Alghamdi, SA Alghamdi, M Suleman - Molecular Diversity, 2024 - Springer
Abstract The Junin virus causes Argentine hemorrhagic fever, leading to severe
complications such as high fever, malaise, muscle pain, and bleeding disorders, including …

Human Riboviruses: A Comprehensive Study

G Mohan, A Choudhury, J Bhat, R Phartyal… - Journal of Molecular …, 2024 - Springer
The urgency to understand the complex interactions between viruses, their animal
reservoirs, and human populations has been necessitated by the continuous spread of …

Molecular mechanisms underlying the cellular entry and host range restriction of Lujo virus

T Saito, T Hattori, K Okuya, R Manzoor, H Miyamoto… - Mbio, 2022 - Am Soc Microbiol
Like other human-pathogenic arenaviruses, Lujo virus (LUJV) is a causative agent of viral
hemorrhagic fever in humans. LUJV infects humans with high mortality rates, but the …