25 years of contrast-enhanced MRI: developments, current challenges and future perspectives

J Lohrke, T Frenzel, J Endrikat, FC Alves, TM Grist… - Advances in …, 2016 - Springer
In 1988, the first contrast agent specifically designed for magnetic resonance imaging (MRI),
gadopentetate dimeglumine (Magnevist®), became available for clinical use. Since then, a …

Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas

JL Boxerman, CC Quarles, LS Hu, BJ Erickson… - Neuro …, 2020 - academic.oup.com
Despite the widespread clinical use of dynamic susceptibility contrast (DSC) MRI, DSC-MRI
methodology has not been standardized, hindering its utilization for response assessment in …

Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures

LS Hu, F D'Angelo, TM Weiskittel, FP Caruso… - Nature …, 2023 - nature.com
Sampling restrictions have hindered the comprehensive study of invasive non-enhancing
(NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present …

Awake surgery for WHO Grade II gliomas within “noneloquent” areas in the left dominant hemisphere: toward a “supratotal” resection

YN Yordanova, S Moritz-Gasser, H Duffau - Journal of neurosurgery, 2011 - thejns.org
Object It has been demonstrated that an extensive resection (total or subtotal) may
significantly increase the overall survival in patients with WHO Grade II gliomas (low-grade …

Gliomas: predicting time to progression or survival with cerebral blood volume measurements at dynamic susceptibility-weighted contrast-enhanced perfusion MR …

M Law, RJ Young, JS Babb, N Peccerelli, S Chheang… - Radiology, 2008 - pubs.rsna.org
Purpose: To retrospectively determine whether relative cerebral blood volume (CBV)
measurements can be used to predict clinical outcome in patients with high-grade gliomas …

Imaging of intratumoral heterogeneity in high-grade glioma

LS Hu, A Hawkins-Daarud, L Wang, J Li, KR Swanson - Cancer letters, 2020 - Elsevier
Abstract High-grade glioma (HGG), and particularly Glioblastoma (GBM), can exhibit
pronounced intratumoral heterogeneity that confounds clinical diagnosis and management …

Comparison of dynamic susceptibility-weighted contrast-enhanced MR methods: recommendations for measuring relative cerebral blood volume in brain tumors

ES Paulson, KM Schmainda - Radiology, 2008 - pubs.rsna.org
Purpose: To investigate whether estimates of relative cerebral blood volume (rCBV) in brain
tumors, obtained by using dynamic susceptibility-weighted contrast material–enhanced …

[HTML][HTML] Clinical neuroimaging using arterial spin-labeled perfusion magnetic resonance imaging

RL Wolf, JA Detre - Neurotherapeutics, 2007 - Elsevier
The two most common methods for measuring perfusion with MRI are based on dynamic
susceptibility contrast (DSC) and arterial spin labeling (ASL). Although clinical experience to …

Diffusion-weighted MR imaging: diagnosing atypical or malignant meningiomas and detecting tumor dedifferentiation

VA Nagar, JR Ye, WH Ng, YH Chan… - American Journal …, 2008 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Atypical and malignant meningiomas are uncommon
tumors with aggressive behavior and higher mortality, morbidity, and recurrence compared …

Principles of T2*‐weighted dynamic susceptibility contrast MRI technique in brain tumor imaging

MS Shiroishi, G Castellazzi… - Journal of magnetic …, 2015 - Wiley Online Library
Dynamic susceptibility contrast magnetic resonance imaging (DSC‐MRI) is used to track the
first pass of an exogenous, paramagnetic, nondiffusible contrast agent through brain tissue …