Recently, in the field of cancer treatment, the paradigm has changed to immunotherapy that
activates the immune system to induce cancer attacks. Among them, immune checkpoint …

The successful outcomes of chimeric antigen receptor (CAR) T-cell therapy in treating
hematologic cancers have increased the previously unprecedented excitement to use this …

In spite of the remarkable progress in basic and preclinical studies of acute myeloid
leukemia (AML), the five-year survival rate of AML patients remains poor, highlighting the …

Simple Summary Primary liver cancer, also known as Hepatocellular carcinoma (HCC), is
considered to be a major global health challenge. Due to delays in diagnosis at early …

Simple Summary Colorectal cancer (CRC) begins when normal cells turn out of balance,
and a tumor is formed in the lining of the colon or rectum. Cytotoxic T-lymphocyte protein 4 …

Immunotherapy is a new pillar of cancer therapy that provides novel opportunities to treat
solid tumors. In this context, the development of new drugs targeting immune checkpoints is …

Immunotherapy is a new type of tumor treatment after surgery, radiotherapy and
chemotherapy, which can be used to manage and destroy tumor cells through activating or …

Immunotherapy can potentially suppress the highly aggressive glioblastoma (GBM) by
promoting T lymphocyte infiltration. Nevertheless, the immune privilege phenomenon …

Chimeric antigen receptor macrophage (CAR-MΦ) represents a significant advancement in
immunotherapy, especially for treating solid tumors where traditional CAR-T therapies face …

Cytokines are important mediators of the immune system, and their secretion level needs to
be carefully regulated, as an unbalanced activity may lead to cytokine release syndromes …