Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents

MA Reddy, N Jain, D Yada, C Kishore… - Journal of medicinal …, 2011 - ACS Publications
A new series of resveratrol analogues was designed, synthesized, and demonstrated to be
tubulin polymerization inhibitors. Most of these compounds exhibited antiproliferative activity …

Magnetically Recoverable CuFe2O4 Nanoparticles: Catalyzed Synthesis of Aryl Azides and 1,4‐Diaryl‐1,2,3‐triazoles from Boronic Acids in Water

AS Kumar, MA Reddy, M Knorn… - European Journal of …, 2013 - Wiley Online Library
Magnetically recoverable and reusable CuFe2O4 nanoparticles are shown to be highly
efficient catalysts for the one‐pot synthesis of biologically important 1, 4‐diaryl‐1, 2, 3 …

Chemo-/Regio-Selective Synthesis of Novel Functionalized Spiro [pyrrolidine-2, 3′-oxindoles] under Microwave Irradiation and Their Anticancer Activity

R Sharma, L Yadav, AA Nasim, RK Yadav, RH Chen… - Molecules, 2023 - mdpi.com
A novel series of nitrostyrene-based spirooxindoles were synthesized via the reaction of
substituted isatins 1a–b, a number of α-amino acids 2a–e and (E)-2-aryl-1-nitroethenes 3a …

Synthesis and biological evaluation of bergenin-1, 2, 3-triazole hybrids as novel class of anti-mitotic agents

PP Kumar, B Siva, BV Rao, GD Kumar, VL Nayak… - Bioorganic …, 2019 - Elsevier
In continuation of our investigation of pharmacologically-motivated natural products, we
have isolated bergenin (1) as a major compound from Mallotus philippensis, which is …

Synthesis and biological evaluation of Schizandrin derivatives as potential anti-cancer agents

D Amujuri, B Siva, B Poornima, K Sirisha… - European journal of …, 2018 - Elsevier
A new series of Schizandrin (1) derivatives were synthesized utilizing the C-9 position of the
Schizandrin core and evaluated for their cytotoxic activities against HeLa (cervical cancer) …

Synthesis of phenstatin/isocombretastatin–chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers

A Kamal, GB Kumar, M Vishnuvardhan… - Organic & …, 2015 - pubs.rsc.org
A series of phenstatin/isocombretastatin–chalcones were synthesized and screened for their
cytotoxic activity against various human cancer cell lines. Some representative compounds …

Synthesis of arylpyrazole linked benzimidazole conjugates as potential microtubule disruptors

A Kamal, AB Shaik, S Polepalli, GB Kumar… - Bioorganic & medicinal …, 2015 - Elsevier
In an attempt to develop potent and selective anticancer agents, a series of twenty
arylpyrazole linked benzimidazole conjugates (10a–t) were designed and synthesized as …

Rational design, chemical synthesis and cellular evaluation of novel 1, 3-diynyl derivatives of noscapine as potent tubulin binding anticancer agents

AK Patel, RK Meher, PK Reddy, RK Pedapati… - Journal of Molecular …, 2021 - Elsevier
We present a new class of derivatives of noscapine, 1, 3-diynyl-noscapinoids of an
antitussive plant alkaloid, noscapine based on our in silico efforts that binds tubulin and …

Adamantyl-tethered-biphenylic compounds induce apoptosis in cancer cells by targeting Bcl homologs

S Anusha, CD Mohan, H Ananda… - Bioorganic & medicinal …, 2016 - Elsevier
Bcl homologs prominently contribute to apoptotic resistance in cancer cells and serve as
molecular targets in treatment of various cancers. Herein, we report the synthesis of biphenyl …

Nanocrystalline Titania‐Supported Palladium (0) Nanoparticles for Suzuki–Miyaura Cross‐Coupling of Aryl and Heteroaryl Halides

B Sreedhar, D Yada, PS Reddy - Advanced Synthesis & …, 2011 - Wiley Online Library
The Suzuki cross‐coupling reaction of various aryl and heteroaryl halides with arylboronic
and heteroarylboronic acids was studied using a titania‐supported palladium (0) catalyst at …