Microfluidics-based systems in diagnosis of Alzheimer's disease and biomimetic modeling

Y Li, D Li, P Zhao, K Nandakumar, L Wang, Y Song - Micromachines, 2020 - mdpi.com
Early detection and accurate diagnosis of Alzheimer's disease (AD) is essential for patient
care and disease treatment. Microfluidic technology is emerging as an economical and …

Use of some cost-effective technologies for a routine clinical pathology laboratory

M Vázquez, L Anfossi, H Ben-Yoav, L Diéguez… - Lab on a Chip, 2021 - pubs.rsc.org
Classically, the need for highly sophisticated instruments with important economic costs has
been a major limiting factor for clinical pathology laboratories, especially in developing …

Exploring sialyl-Tn expression in microfluidic-isolated circulating tumour cells: A novel biomarker and an analytical tool for precision oncology applications

M Neves, R Azevedo, L Lima, MI Oliveira, A Peixoto… - New biotechnology, 2019 - Elsevier
Circulating tumour cells (CTCs) originating from a primary tumour, lymph nodes and distant
metastases hold great potential for liquid biopsies by providing a molecular fingerprint for …

Circulating tumor cells in bladder cancer: Emerging technologies and clinical implications foreseeing precision oncology

R Azevedo, J Soares, A Peixoto, S Cotton… - … oncology: seminars and …, 2018 - Elsevier
Context Circulating tumor cells (CTC) in peripheral blood of cancer patients provide an
opportunity for real-time liquid biopsies capable of aiding early intervention, therapeutic …

Fluorescence signal amplification by optical reflection in metal-coated nanowells

S Mahmud, D Dutta - Microchimica Acta, 2022 - Springer
A significant amplification in the fluorescence signal is demonstrated when measured in
metal (aluminum)-coated fluidic wells with volumes on the order of a nanoliter or smaller …

Catch and release: integrated system for multiplexed detection of bacteria

J Verbarg, WD Plath, LC Shriver-Lake… - Analytical …, 2013 - ACS Publications
An integrated system with automated immunomagnetic separation and processing of fluidic
samples was demonstrated for multiplexed optical detection of bacterial targets. Mixtures of …

The effects of external magnetic fields on the flow and heat transfer in a three-dimensional microchannel

A Sohankar, M Gharehkhani - Numerical Heat Transfer, Part A …, 2023 - Taylor & Francis
In this study, the thermal and flow characteristics in a U-type microchannel have been
investigated and compared under the influence of single and combined magnetic fields. The …

Advances and Future Trends in the Detection of Beta-Amyloid: A Comprehensive Review

A Ganguly, SS Babu, S Ghosh, R Velyutham… - Medical Engineering & …, 2024 - Elsevier
The neurodegenerative condition known as Alzheimer's disease is typified by the build-up of
beta-amyloid plaques within the brain. The timely and precise identification of beta-amyloid …

Microdevice in cellular pathology: microfluidic platforms for fluorescence in situ hybridization and analysis of circulating tumor cells

K Sato - Analytical Sciences, 2015 - jstage.jst.go.jp
Microfluidic devices enable the miniaturization, integration, automation, and parallelization
of chemical and biochemical processes. This new technology also provides opportunity for …

Liquid phase detection in the miniature scale. Microfluidic and capillary scale measurement and separation systems. A tutorial review

CG Warren, PK Dasgupta - Analytica Chimica Acta, 2024 - Elsevier
Microfluidic and capillary devices are increasingly being used in analytical applications
while their overall size keeps decreasing. Detection sensitivity for these microdevices gains …