The role of lipopolysaccharide-induced cell signalling in chronic inflammation
Lipopolysaccharide (LPS) is the main structural component of the outer membrane of most
Gram-negative bacteria and has diverse immunostimulatory and procoagulant effects. Even …
Gram-negative bacteria and has diverse immunostimulatory and procoagulant effects. Even …
Dysbiosis of gut microbiota and microbial metabolites in Parkinson's Disease
MF Sun, YQ Shen - Ageing research reviews, 2018 - Elsevier
Gut microbial dysbiosis and alteration of microbial metabolites in Parkinson's disease (PD)
have been increasingly reported. Dysbiosis in the composition and abundance of gut …
have been increasingly reported. Dysbiosis in the composition and abundance of gut …
An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson's disease participants
DA Hall, RM Voigt, TM Cantu-Jungles… - Nature …, 2023 - nature.com
A pro-inflammatory intestinal microbiome is characteristic of Parkinson's disease (PD).
Prebiotic fibers change the microbiome and this study sought to understand the utility of …
Prebiotic fibers change the microbiome and this study sought to understand the utility of …
Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice
Objective Recent evidence suggesting an important role of gut-derived inflammation in brain
disorders has opened up new directions to explore the possible role of the gut-brain axis in …
disorders has opened up new directions to explore the possible role of the gut-brain axis in …
Intestinal dysbiosis and lowered serum lipopolysaccharide-binding protein in Parkinson's disease
Background The intestine is one of the first affected organs in Parkinson's disease (PD). PD
subjects show abnormal staining for Escherichia coli and α-synuclein in the colon. Methods …
subjects show abnormal staining for Escherichia coli and α-synuclein in the colon. Methods …
The endotoxin hypothesis of Parkinson's disease
The endotoxin hypothesis of Parkinson's disease (PD) is the idea that lipopolysaccharide
(LPS) endotoxins contribute to the pathogenesis of this disorder. LPS endotoxins are found …
(LPS) endotoxins contribute to the pathogenesis of this disorder. LPS endotoxins are found …
Biomarkers of sepsis
JD Faix - Critical reviews in clinical laboratory sciences, 2013 - Taylor & Francis
Sepsis is an unusual systemic reaction to what is sometimes an otherwise ordinary infection,
and it probably represents a pattern of response by the immune system to injury. A hyper …
and it probably represents a pattern of response by the immune system to injury. A hyper …
Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder of aging.
The pathological hallmark of PD is neuronal inclusions termed Lewy bodies whose main …
The pathological hallmark of PD is neuronal inclusions termed Lewy bodies whose main …
Enteric α-synuclein impairs intestinal epithelial barrier through caspase-1-inflammasome signaling in Parkinson's disease before brain pathology
C Pellegrini, V D'Antongiovanni, F Miraglia… - npj Parkinson's …, 2022 - nature.com
Abstracts Bowel inflammation, impaired intestinal epithelial barrier (IEB), and gut dysbiosis
could represent early events in Parkinson's disease (PD). This study examined, in a …
could represent early events in Parkinson's disease (PD). This study examined, in a …
[HTML][HTML] Alcoholic liver disease and the gut-liver axis
G Szabo, S Bala - World journal of gastroenterology: WJG, 2010 - ncbi.nlm.nih.gov
Alcoholic liver disease (ALD) is one of the leading causes of liver diseases and liver-related
death worldwide. Of the many factors that contribute to the pathogenesis of ALD, gut-derived …
death worldwide. Of the many factors that contribute to the pathogenesis of ALD, gut-derived …