Systemic inflammation as a therapeutic target in acute ischemic stroke

T Dziedzic - Expert review of neurotherapeutics, 2015 - Taylor & Francis
Acute systemic inflammatory reaction superimposed on chronic low-grade inflammation
accompanies acute ischemic stroke. Elevated blood levels of systemic inflammatory markers …

C-reactive protein triggers cell death in ischemic cells

A Sheriff, S Kayser, P Brunner, B Vogt - Frontiers in immunology, 2021 - frontiersin.org
C-reactive protein (CRP) is the best-known acute phase protein. In humans, almost every
type of inflammation is accompanied by an increase of CRP concentration. Until recently, the …

Inflammation and ischaemic stroke

KW Muir, P Tyrrell, N Sattar… - Current opinion in …, 2007 - journals.lww.com
Inflammation is implicated in several aspects of acute ischaemic stroke. It remains to be
established whether the inflammatory response is a truly independent risk factor in general …

Blood biomarkers in the diagnosis of ischemic stroke: a systematic review

W Whiteley, MC Tseng, P Sandercock - Stroke, 2008 - Am Heart Assoc
Background and Purpose—The diagnosis of ischemic stroke can be difficult. CT may be
normal in the early stages of ischemic stroke or in patients with minor symptoms and MR is …

C-reactive protein in the very early phase of acute ischemic stroke: association with poor outcome and death

HM Den Hertog, JA Van Rossum, HB Van Der Worp… - Journal of …, 2009 - Springer
Acute ischemic stroke may trigger an inflammatory response that leads to increased levels of
C-reactive protein (CRP). High levels of CRP may be associated with poor outcome …

Admission C–reactive protein after acute ischemic stroke is associated with stroke severity and mortality: The'Bergen stroke study'

TT Idicula, J Brogger, H Naess, U Waje-Andreassen… - BMC neurology, 2009 - Springer
Background There is growing evidence that inflammation plays an important role in
atherogenesis. Previous studies show that C-reactive protein (CRP), an inflammatory …

Inflammation biomarkers are associated with the incidence of cardiovascular disease: a meta-analysis

Y Liu, S Guan, H Xu, N Zhang, M Huang… - Frontiers in …, 2023 - frontiersin.org
Background Inflammation is a risk factor for cardiovascular disease (CVD), and particular
inflammatory parameters can be used to predict the incidence of CVD. The aim of this study …

Molecular biomarkers in stroke diagnosis and prognosis

MB Maas, KL Furie - Biomarkers in medicine, 2009 - Taylor & Francis
Serum biomarkers related to the cascade of inflammatory, hemostatic, glial and neuronal
perturbations have been identified to diagnose and characterize intracerebral hemorrhage …

[HTML][HTML] Blood/brain biomarkers of inflammation after stroke and their association with outcome: from C-reactive protein to damage-associated molecular patterns

A Bustamante, A Simats, A Vilar-Bergua… - …, 2016 - Elsevier
Stroke represents one of the most important causes of disability and death in developed
countries. However, there is a lack of prognostic tools in clinical practice to monitor the …

C-reactive protein and long-term ischemic stroke prognosis

RL VanGilder, DM Davidov, KR Stinehart… - Journal of Clinical …, 2014 - Elsevier
C-reactive protein (CRP) is an inflammatory biomarker of inflammation and may reflect
progression of vascular disease. Conflicting evidence suggests CRP may be a prognostic …