Glycosylation of proteins is one of the most important PTMs, with more than half of all human
proteins estimated to be glycosylated. It is widely known that aberrant glycosylation has …

The skeleton is one of the most common sites for metastatic cancer, and tumors arising from
the breast or prostate possess an increased propensity to spread to this site. The growth of …

Tumor cells exhibit striking changes in cell surface glycosylation as a consequence of
dysregulated glycosyltransferases and glycosidases. In particular, an increase in the …

Gangliosides are acidic glycosphingolipids containing one or more sialic acid residues.
They are essential compounds at the outer leaflet of the plasma membrane, where they …

The glycome acts as an essential interface between cells and the surrounding
microenvironment. However, changes in glycosylation occur in nearly all breast cancers …

The enhanced expression of nitric oxide (• NO) synthase predicts triple-negative breast
cancer outcome and its resistance to different therapeutics. Our earlier work demonstrated …

Aberrant glycosylation in tumours stem from altered glycosyltransferase (GT) gene
expression but can the expression profiles of these signature genes be used to classify …

Heterogeneity in phenotypes of malignantly transformed cells and aberrant glycan
expression on their surface are two prominent hallmarks of cancers that have hitherto not …

Background Altered glycosylation associated with hepatocellular carcinoma (HCC) is well
documented. However, few reports have investigated the association between …

Modifications in cell surface glycosylation affecting cell adhesion are common
characteristics of transformed cells. This study characterizes the N-glycosylation profile of E …