Despite the high prevalence of performance-enhancing drug (PED) use, media attention has
focused almost entirely on PED use by elite athletes to illicitly gain a competitive advantage …

Increasing evidence points to an association between major depressive disorders (MDDs)
and diverse types of GABAergic deficits. In this review, we summarize clinical and preclinical …

Introduction The aim of this article is to review the physiology of progesterone and focus on
its physiological actions on tissues such as endometrium, uterus, mammary gland …

Aggressive behavior is observed in many animal species, such as insects, fish, lizards,
frogs, and most mammals including humans. This wide range of conservation underscores …

Neuroactive steroids synthesized in neuronal tissue, referred to as neurosteroids, are
implicated in proliferation, differentiation, activity and survival of nerve cells. Neurosteroids …

Progesterone, the ovarian steroid hormone, regulates a plentitude of biological processes in
tissues ranging from the brain to bones. Recognizing the role of progesterone and its …

Aggression is a key component for social behaviour and can have an adaptive value or
deleterious consequences. Here, we review the role of sex-related differences in aggressive …

Allopregnanolone is synthesized in the central nervous system either de novo from
cholesterol or from steroid hormone precursors like progesterone and pregnenolone. Over …

Abstract Major Depressive Disorder (MDD) or depression is a pathological mental condition
affecting millions of people worldwide. Identification of objective biological markers of …

Anabolic-androgenic steroids (AAS) are synthetic substances derived from testosterone that
are largely employed due to their trophic effect on muscle tissue of athletes at all levels …