Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Enzymes are complex biological catalysts and are critical to life. Most oxidations of
chemicals are catalyzed by cytochrome P450 (P450, CYP) enzymes, which generally utilize …

Membrane proteins have long presented a challenge to biochemical and functional studies.
In the absence of a bilayer environment, individual proteins and critical macromolecular …

Membrane proteins are involved in numerous vital biological processes, including transport,
signal transduction and the enzymes in a variety of metabolic pathways. Integral membrane …

Many oxidation–reduction (redox) enzymes, particularly oxygenases, have roles in reactions
that make and break C–C bonds. The list includes cytochrome P450 and other heme-based …

Heme-copper oxidases (HCOs) are terminal enzymes on the mitochondrial or bacterial
respiratory electron transport chain, which utilize a unique heterobinuclear active site to …

The P450 enzyme CYP121 from Mycobacterium tuberculosis catalyzes a carbon–carbon (C–
C) bond coupling cyclization of the dityrosine substrate containing a diketopiperazine ring …

The cytochrome P450 (CYP) superfamily of heme monooxygenases has demonstrated
ability to facilitate hydroxylation, desaturation, sulfoxidation, epoxidation, heteroatom …

The 14α‐demethylation step is critical in eukaryotic sterol biosynthesis, catalyzed by
cytochrome P450 (P450) Family 51 enzymes, for example, with lanosterol in mammals. This …