Synthetic epigenetics-assisted microbial chassis engineering

I Komera, C Gao, X Chen, W Chen, L Liu - Trends in Microbiology, 2023 - cell.com
Microbial chassis engineering is the milestone of efficient biotechnological applications.
However, microbial chassis cell engineering is adversely affected by (i) regulatory tool …

Microbial Synthetic Epigenetic Tools Design and Applications

I Komera, X Chen, L Liu, C Gao - ACS Synthetic Biology, 2024 - ACS Publications
Microbial synthetic epigenetics offers significant opportunities for the design of synthetic
biology tools by leveraging reversible gene control mechanisms without altering DNA …

[HTML][HTML] Synthetic Interventions in Epigenome: Unraveling Chromatin's Potential for Therapeutic Applications

J Kim, J Kim, M Park - Current Opinion in Systems Biology, 2024 - Elsevier
The epigenome, comprising DNA and histone modifications alongside intricate chromatin
structures, has emerged as pivotal players in disease development. These factors offer …

Who is winning the war: Science or the adaptive molecular mechanisms of bacteria, evolving to survive antibiotic therapy?

JAG Salazar, JRM Díaz, JGT Ferrara - Gene Reports, 2024 - Elsevier
The battle against bacterial resistance to antibiotics is currently being lost. The present
analysis suggests the importance of epigenetics in the evolution of bacterial resistance …

Natural Product-Based Treatment of Ear Infection

S Lenka, SK Swain, D Dubey - Natural Products for Antibacterial Drug …, 2024 - Springer
Otitis media (OM) has a complex anatomy and numerous presentations in children
worldwide, especially in developing countries. A rising number of alternative treatments …

[PDF][PDF] A hybrid population model enables the study of single-cell heterogeneity in an epigenetic memory system.

V Klingel, D Graf, S Weirich, A Jeltsch, N Radde - simtech2023.uni-stuttgart.de
Single-cells measurement techniques like flow cytometry allow heterogeneity in biological
systems to be quantified efficiently. However, many modelling approaches currently cannot …