Stroke and late-onset Alzheimer's disease (AD) are risk factors for each other; the
comorbidity of these brain disorders in aging individuals represents a significant challenge …

Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates …

The blood–brain barrier (BBB) keeps neurotoxic plasma-derived components, cells, and
pathogens out of the brain. An early BBB breakdown and/or dysfunction have been shown in …

In Alzheimer's disease (AD), memory impairment is the most prominent feature that afflicts
patients and their families. Although reactive astrocytes have been observed around …

The goal of this review is to discuss how behavioral tests in mice relate to the pathological
and neuropsychological features seen in human Alzheimer's disease (AD), and present a …

Alzheimer's disease (AD), the leading cause of dementia worldwide, is characterized by the
accumulation of the β-amyloid peptide (Aβ) within the brain along with hyperphosphorylated …

Alzheimer's disease (AD) is a neurodegenerative disorder that nowadays affects more than
40 million people worldwide and it is predicted to exponentially increase in the coming …

Autism is a heterogeneous neurodevelopmental disorder of unknown aetiology that affects 1
in 100–150 individuals. Diagnosis is based on three categories of behavioural criteria …

In its earliest clinical phase, Alzheimer's disease characteristically produces a remarkably
pure impairment of memory. Mounting evidence suggests that this syndrome begins with …

Although extensive data support a central pathogenic role for amyloid β protein (Aβ) in
Alzheimer's disease, the amyloid hypothesis remains controversial, in part because a …