Tea is the most widely used beverage worldwide. Japanese and Chinese people have been
drinking tea for centuries and in Asia, it is the most consumed beverage besides water. It is a …

Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

The resistance of cancer cells to chemotherapeutic drugs greatly reduces the therapeutic
effect in cancer patients, and the toxic side effects caused by chemotherapy also seriously …

Cancer is still one of the most widespread diseases globally, it is considered a vital health
challenge worldwide and one of the main barriers to long life expectancy. Due to the …

Phytochemicals play a pivotal role in human health and drug discovery. The safety
evaluation of plant extracts is a prerequisite to ensure that all phytochemicals are safe …

Background Cisplatin (DDP) resistance is a key problem for effective treatment of gastric
cancer (GC). Circular RNA PVT1 (circPVT1) acts as a vital regulator in the progression and …

Abstract Epigallocatechin‑3‑gallate (EGCG), a polyphenol present in green tea, exhibits
anticancer effects in various types of cancer. A number of studies have focused on the …

Despite DNA methylation occurred in acute kidney injury (AKI), how it influenced
progression of AKI remains unclear. Methyl-CpG-binding domain protein 2 (MBD2), a …

Doxorubicin (DOX), the first-line chemotherapy for bladder cancer, usually induces side
effects. We previously demonstrated that green tea polyphenol EGCG had potent anti-tumor …

Background Cyclophosphamide (CTX), which has been used to treat common female
cancers for several years, often causes ovarian damage, early menopause and infertility …