Meiotic recombination in mammals: localization and regulation
F Baudat, Y Imai, B De Massy - Nature Reviews Genetics, 2013 - nature.com
During meiosis, a programmed induction of DNA double-strand breaks (DSBs) leads to the
exchange of genetic material between homologous chromosomes. These exchanges …
exchange of genetic material between homologous chromosomes. These exchanges …
Mechanism and regulation of meiotic recombination initiation
I Lam, S Keeney - Cold Spring Harbor perspectives in …, 2015 - cshperspectives.cshlp.org
Meiotic recombination involves the formation and repair of programmed DNA double-strand
breaks (DSBs) catalyzed by the conserved Spo11 protein. This review summarizes recent …
breaks (DSBs) catalyzed by the conserved Spo11 protein. This review summarizes recent …
Characterizing mutagenic effects of recombination through a sequence-level genetic map
INTRODUCTION Diversity in the sequence of the human genome, arising from
recombinations and mutations, is fundamental to human evolution and human diversity …
recombinations and mutations, is fundamental to human evolution and human diversity …
Genetics of human female infertility
SA Yatsenko, A Rajkovic - Biology of reproduction, 2019 - academic.oup.com
About 10% of women of reproductive age are unable to conceive or carry a pregnancy to
term. Female factors alone account for at least 35% of all infertility cases and comprise a …
term. Female factors alone account for at least 35% of all infertility cases and comprise a …
Self-organization of meiotic recombination initiation: general principles and molecular pathways
Recombination in meiosis is a fascinating case study for the coordination of chromosomal
duplication, repair, and segregation with each other and with progression through a cell …
duplication, repair, and segregation with each other and with progression through a cell …
Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape
Background Previously, a role was demonstrated for transcription in the acquisition of DNA
methylation at imprinted control regions in oocytes. Definition of the oocyte DNA methylome …
methylation at imprinted control regions in oocytes. Definition of the oocyte DNA methylome …
Cause and consequence of cancer/testis antigen activation in cancer
AW Whitehurst - Annual review of pharmacology and toxicology, 2014 - annualreviews.org
Tumor cells frequently exhibit widespread epigenetic aberrations that significantly alter the
repertoire of expressed proteins. In particular, it has been known for nearly 25 years that …
repertoire of expressed proteins. In particular, it has been known for nearly 25 years that …
The meiotic checkpoint network: step-by-step through meiotic prophase
VV Subramanian… - Cold Spring Harbor …, 2014 - cshperspectives.cshlp.org
The generation of haploid gametes by meiosis is a highly conserved process for sexually
reproducing organisms that, in almost all cases, involves the extensive breakage of …
reproducing organisms that, in almost all cases, involves the extensive breakage of …
Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia
C Xie, W Wang, C Tu, L Meng, G Lu… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Meiosis is an essential stage in the life cycle of sexually reproducing
species, underlying formation of haploid gametes and serving as the basis of genetic …
species, underlying formation of haploid gametes and serving as the basis of genetic …
[HTML][HTML] Molecular control of rodent spermatogenesis
Spermatogenesis is a complex developmental process that ultimately generates mature
spermatozoa. This process involves a phase of proliferative expansion, meiosis, and …
spermatozoa. This process involves a phase of proliferative expansion, meiosis, and …