GAD antibodies in neurological disorders—insights and challenges
F Graus, A Saiz, J Dalmau - Nature Reviews Neurology, 2020 - nature.com
Antibodies to glutamic acid decarboxylase (GAD) have been associated with several
neurological syndromes, including stiff-person syndrome, cerebellar ataxia and epilepsy …
neurological syndromes, including stiff-person syndrome, cerebellar ataxia and epilepsy …
Antiglutamic acid decarboxylase 65 (GAD65) antibody-associated epilepsy
Glutamic acid decarboxylase (GAD) antibody-associated encephalitis causes both acute
seizures and chronic epilepsy with predominantly temporal lobe onset. This condition is …
seizures and chronic epilepsy with predominantly temporal lobe onset. This condition is …
Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: a case series, characterisation of the antigen, and analysis of the …
M Petit-Pedrol, T Armangue, X Peng, L Bataller… - The lancet …, 2014 - thelancet.com
Background Increasing evidence suggests that seizures and status epilepticus can be
immune-mediated. We aimed to describe the clinical features of a new epileptic disorder …
immune-mediated. We aimed to describe the clinical features of a new epileptic disorder …
Cerebral FDG-PET and MRI findings in autoimmune limbic encephalitis: correlation with autoantibody types
A Baumgartner, S Rauer, I Mader, PT Meyer - Journal of neurology, 2013 - Springer
In parallel to the detection of new neuronal autoantibodies, the diagnosis of non-infectious
limbic encephalitis has risen. Given that cerebral imaging studies show highly variable …
limbic encephalitis has risen. Given that cerebral imaging studies show highly variable …
Neuropathological mechanisms of seizures in autism spectrum disorder
This manuscript reviews biological abnormalities shared by autism spectrum disorder (ASD)
and epilepsy. Two neuropathological findings are shared by ASD and epilepsy …
and epilepsy. Two neuropathological findings are shared by ASD and epilepsy …
The neurological syndromes associated with glutamic acid decarboxylase antibodies
JF Baizabal-Carvallo - Journal of autoimmunity, 2019 - Elsevier
A number of neurological syndromes have been described in patients with positive serum
antibodies (Abs) against the enzyme glutamic acid decarboxylase (GAD), the rate limiting …
antibodies (Abs) against the enzyme glutamic acid decarboxylase (GAD), the rate limiting …
[HTML][HTML] Antibody-mediated autoimmune encephalopathies and immunotherapies
M Gastaldi, A Thouin, A Vincent - Neurotherapeutics, 2016 - Elsevier
Over the last 15 years it has become clear that rare but highly recognizable diseases of the
central nervous system (CNS), including newly identified forms of limbic encephalitis and …
central nervous system (CNS), including newly identified forms of limbic encephalitis and …
Prevalence and immunological spectrum of temporal lobe epilepsy with glutamic acid decarboxylase antibodies
Background and purpose: High levels of glutamic acid decarboxylase (GAD)‐ab were
initially described in patients with stiff person syndrome, and have since also been observed …
initially described in patients with stiff person syndrome, and have since also been observed …
[HTML][HTML] Treatment of immune-mediated temporal lobe epilepsy with GAD antibodies
MP Malter, C Frisch, H Zeitler, R Surges, H Urbach… - Seizure, 2015 - Elsevier
Purpose Temporal lobe epilepsy with antibodies (abs) against the glutamic acid
decarboxylase 65 isoform (GAD-TLE) is known as an immune-mediated neurological …
decarboxylase 65 isoform (GAD-TLE) is known as an immune-mediated neurological …
Metabolic topography of autoimmune non-paraneoplastic encephalitis
Abstract Purpose F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) is
emerging to be a useful tool in supporting the diagnosis of AIE. In this study, we describe the …
emerging to be a useful tool in supporting the diagnosis of AIE. In this study, we describe the …