[HTML][HTML] Zebrafish as a model for inflammation and drug discovery

R Zanandrea, CD Bonan, MM Campos - Drug Discovery Today, 2020 - Elsevier
Highlights•Zebrafish are a useful tool for screening new drugs for inflammation.•This teleost
shares several inflammatory mediators and receptors with mammals.•The real-time …

Zebrafish as an emerging model organism to study angiogenesis in development and regeneration

MN Chávez, G Aedo, FA Fierro, ML Allende… - Frontiers in …, 2016 - frontiersin.org
Angiogenesis is the process through which new blood vessels are formed from preexisting
ones and plays a critical role in several conditions including embryonic development, tissue …

Oxidative effects during irreversible electroporation of melanoma cells—In vitro study

W Szlasa, A Kiełbik, A Szewczyk, N Rembiałkowska… - Molecules, 2020 - mdpi.com
Irreversible electroporation (IRE) is today used as an alternative to surgery for the excision of
cancer lesions. This study aimed to investigate the oxidative and cytotoxic effects the cells …

A microfluidic neuronal platform for neuron axotomy and controlled regenerative studies

Z Tong, M Segura-Feliu, O Seira, A Homs-Corbera… - RSC …, 2015 - pubs.rsc.org
Understanding the basic mechanisms of neural regeneration after injury is a pre-requisite for
developing appropriate treatments. Traditional approaches to model axonal lesions, such as …

Satellite glial cell manipulation prior to axotomy enhances developing dorsal root ganglion central branch regrowth into the spinal cord

RI Brown, HM Barber, S Kucenas - Glia, 2024 - Wiley Online Library
The central and peripheral nervous systems (CNS and PNS, respectively) exhibit
remarkable diversity in the capacity to regenerate following neuronal injury with PNS injuries …

Current advances in comprehending dynamics of regenerating axons and axon–glia interactions after peripheral nerve injury in zebrafish

D Gonzalez, ML Allende - International Journal of Molecular Sciences, 2021 - mdpi.com
Following an injury, axons of both the central nervous system (CNS) and peripheral nervous
system (PNS) degenerate through a coordinated and genetically conserved mechanism …

Axon-Schwann cell interactions during peripheral nerve regeneration in zebrafish larvae

ML Ceci, C Mardones-Krsulovic, M Sánchez… - Neural …, 2014 - Springer
Background Peripheral nerve injuries can severely affect the way that animals perceive
signals from the surrounding environment. While damage to peripheral axons generally has …

Cellular dynamics during spinal cord regeneration in larval zebrafish

C Anguita-Salinas, M Sánchez, RA Morales… - Developmental …, 2019 - karger.com
The study of spinal cord regeneration using diverse animal models, which range from null to
robust regenerative capabilities, is imperative for understanding how regeneration evolved …

Confocal microscope-based laser ablation and regeneration assay in zebrafish interneuromast cells

BA Volpe, TH Fotino, AB Steiner - JoVE (Journal of Visualized …, 2020 - jove.com
Hair cells are mechanosensory cells that mediate the sense of hearing. These cells do not
regenerate after damage in humans, but they are naturally replenished in non-mammalian …

Epimedin B exerts an anti-inflammatory effect by regulating the MAPK/NF-κB/NOD-like receptor signalling pathways

L Liu, Y Zhong, T Zheng, J Zhao, S Ding, J Lv… - Fish & Shellfish …, 2024 - Elsevier
Epimedin B (EB), a predominant compound found in Herba Epimedii, has been shown to be
effective in the treatment of osteoporosis and peripheral neuropathy. However, the anti …