In recent years, many promising nanotechnological approaches to biomedical research
have been developed in order to increase implementation of regenerative medicine and …

Extracellular vesicles (EV), which include exosomes and microvesicles, are secreted from
virtually every cell. EV contain mRNA, miRNA, lipids and proteins and can deliver this …

The loss of retinal ganglion cells (RGC) and their axons is one of the leading causes of
blindness and includes traumatic (optic neuropathy) and degenerative (glaucoma) eye …

Photoreceptor apoptosis is recognized as one key pathogenesis of retinal degeneration, the
counteraction of which represents a promising approach to safeguard visual function …

Abstract Background Mesenchymal stem cells (MSCs) have been explored as promising
tools for treatment of several neurological and neurodegenerative diseases. MSCs release …

Purpose: To investigate the benefit of bone marrow mesenchymal stem cell (BMSC)-derived
small extracellular vesicles (sEV) as an intravitreal (ivit) therapy in two rat models of …

Retinal degenerative diseases, such as age-related macular degeneration, retinitis
pigmentosa, diabetic retinopathy or glaucoma, represent the main causes of a decreased …

Abstract Mesenchymal Stem Cells (MSCs) have been studied extensively for the treatment
of several retinal diseases. The therapeutic potential of MSCs lies in its ability to differentiate …

Background The development of new treatment strategies to improve peripheral nerve
repair after injury, especially those that accelerate axonal nerve regeneration, is very …

Glaucoma is considered to be one of the biggest health problems in the world. It is the main
cause of preventable blindness due to its asymptomatic nature in the early stages on the …