An update on current pharmacotherapeutic options for the treatment of ulcerative colitis

F Ferretti, R Cannatelli, MC Monico, G Maconi… - Journal of Clinical …, 2022 - mdpi.com
The main goals of Ulcerative Colitis (UC) treatment are to both induce and maintain the
clinical and endoscopic remission of disease, reduce the incidence of complications such as …

The IL23-IL17 immune axis in the treatment of ulcerative colitis: successes, defeats, and ongoing challenges

D Noviello, R Mager, G Roda, RG Borroni… - Frontiers in …, 2021 - frontiersin.org
Ulcerative colitis (UC) is a chronic relapsing disorder of the colonic tract, characterized by a
dysregulated innate and adaptive immune response to gut microbiota that contributes to the …

ECCO guidelines on inflammatory bowel disease and malignancies

H Gordon, L Biancone, G Fiorino… - Journal of Crohn's …, 2023 - academic.oup.com
This guideline is the second European Crohn's and Colitis Organisation [ECCO] evidence-
based consensus on inflammatory bowel disease [IBD] and malignancy, and is an update …

Ustekinumab treatment in ulcerative colitis: Real‐world data from the Swedish inflammatory bowel disease quality register

J Thunberg, O Björkqvist, CRH Hedin… - United European …, 2022 - Wiley Online Library
Background Real‐world data on clinical outcomes of ustekinumab in ulcerative colitis are
lacking. Objective To assess short‐and long‐term clinical outcomes of ustekinumab in …

Management of non-response and loss of response to anti-tumor necrosis factor therapy in inflammatory bowel disease

J Marsal, M Barreiro-de Acosta, I Blumenstein… - Frontiers in …, 2022 - frontiersin.org
Anti-tumor necrosis factor (anti-TNF) therapy has been successfully used as first-line
biologic treatment for moderate-to-severe inflammatory bowel disease (IBD), in both “step …

Risk of cancer in patients with inflammatory bowel diseases and keys for patient management

V Laredo, S García-Mateo, SJ Martínez-Domínguez… - Cancers, 2023 - mdpi.com
Simple Summary Inflammatory Bowel Diseases (IBDs) are increasingly prevalent
pathologies due to the rise in incidence in some geographic areas and the improvement in …

Precision medicine and drug optimization in adult inflammatory bowel disease patients

S Vieujean, E Louis - Therapeutic Advances in …, 2023 - journals.sagepub.com
Inflammatory bowel diseases (IBD) encompass two main entities including ulcerative colitis
and Crohn's disease. Although having a common global pathophysiological mechanism …

Meta‐analysis: Real‐world effectiveness and safety of ustekinumab in patients with ulcerative colitis

C Taxonera, D Olivares… - Alimentary …, 2023 - Wiley Online Library
Background Evidence on real‐world outcomes of ustekinumab for ulcerative colitis (UC)
patients is needed. Aims To summarise evidence on the real‐world outcomes of …

One-year effectiveness and safety of ustekinumab in ulcerative colitis: a multicenter real-world study from Italy

MF Chiappetta, A Viola, M Mastronardi… - Expert Opinion on …, 2021 - Taylor & Francis
Background Efficacy and safety of ustekinumab for the treatment of ulcerative colitis (UC)
has been demonstrated in clinical trials, but few real-world data are available so far. The aim …

Extraintestinal cancers in inflammatory bowel disease: A literature review

A Massano, L Bertin, F Zingone, A Buda, P Visaggi… - Cancers, 2023 - mdpi.com
Simple Summary Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory
bowel diseases that affect the gut and extraintestinal organs. Preliminary evidence has …