Circadian rhythms and disorders of the timing of sleep

N Meyer, AG Harvey, SW Lockley, DJ Dijk - The Lancet, 2022 - thelancet.com
The daily alternation between sleep and wakefulness is one of the most dominant features
of our lives and is a manifestation of the intrinsic 24 h rhythmicity underlying almost every …

Chronotype and social jetlag: a (self-) critical review

T Roenneberg, LK Pilz, G Zerbini, EC Winnebeck - Biology, 2019 - mdpi.com
The Munich ChronoType Questionnaire (MCTQ) has now been available for more than 15
years and its original publication has been cited 1240 times (Google Scholar, May 2019) …

Circadian mechanisms in medicine

R Allada, J Bass - New England Journal of Medicine, 2021 - Mass Medical Soc
Circadian Mechanisms in Medicine Molecular insights into diurnal variations in human
physiology and behavior are extending our understanding of a wide range of disease …

Circadian clocks and insulin resistance

DJ Stenvers, FAJL Scheer, P Schrauwen… - Nature Reviews …, 2019 - nature.com
Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …

Importance of circadian timing for aging and longevity

VA Acosta-Rodríguez, F Rijo-Ferreira, CB Green… - Nature …, 2021 - nature.com
Dietary restriction (DR) decreases body weight, improves health, and extends lifespan. DR
can be achieved by controlling how much and/or when food is provided, as well as by …

[HTML][HTML] Perfect timing: circadian rhythms, sleep, and immunity—an NIH workshop summary

JA Haspel, R Anafi, MK Brown, N Cermakian… - JCI insight, 2020 - ncbi.nlm.nih.gov
Recent discoveries demonstrate a critical role for circadian rhythms and sleep in immune
system homeostasis. Both innate and adaptive immune responses—ranging from leukocyte …

Circadian disruption: What do we actually mean?

C Vetter - European Journal of Neuroscience, 2020 - Wiley Online Library
The circadian system regulates physiology and behavior. Acute challenges to the system,
such as those experienced when traveling across time zones, will eventually result in re …

Wearable technologies for developing sleep and circadian biomarkers: a summary of workshop discussions

CM Depner, PC Cheng, JK Devine, S Khosla… - sleep, 2020 - academic.oup.com
Abstract The “International Biomarkers Workshop on Wearables in Sleep and Circadian
Science” was held at the 2018 SLEEP Meeting of the Associated Professional Sleep …

High-accuracy determination of internal circadian time from a single blood sample

N Wittenbrink, B Ananthasubramaniam… - The Journal of …, 2018 - Am Soc Clin Investig
BACKGROUND. The circadian clock is a fundamental and pervasive biological program that
coordinates 24-hour rhythms in physiology, metabolism, and behavior, and it is essential to …

Circadian disruption, clock genes, and metabolic health

LA Schrader, SM Ronnekleiv-Kelly… - The Journal of Clinical …, 2024 - jci.org
A growing body of research has identified circadian-rhythm disruption as a risk factor for
metabolic health. However, the underlying biological basis remains complex, and complete …