Thermodynamics and Kinetics‐Directed Regulation of Nucleic Acid‐Based Molecular Recognition

Y Liu, Z Zhao, Y Zeng, M He, Y Lyu, Q Yuan - Small Methods, 2024 - Wiley Online Library
Nucleic acid‐based molecular recognition plays crucial roles in various fields like
biosensing and disease diagnostics. To achieve optimal detection and analysis, it is …

Work distribution for unzipping processes

P Werner, AK Hartmann, SN Majumdar - Physical Review E, 2024 - APS
A simple zipper model is introduced, representing in a simplified way, eg, the folded DNA
double helix or hairpin structures in RNA. The double stranded hairpin is connected to a …

Nonequilibrium work relations for energy and information

F Ritort - arXiv preprint arXiv:2404.04582, 2024 - arxiv.org
arXiv:2404.04582v1 [physics.bio-ph] 6 Apr 2024 Page 1 Nonequilibrium work relations for
energy and information Felix Ritort∗ Small Biosystems Lab, Condensed Matter Physics …

Statistical Physics of Biological Molecules

S Cocco, A De Martino, A Pagnani… - Spin Glass Theory and …, 2023 - World Scientific
This chapter reviews the use of statistical mechanics techniques, and in particular those
inspired by disordered systems and spin glasses, for the study of biological molecules. In a …

Optical Tweezers to Force Information out of Biological and Synthetic Systems One Molecule at a Time

R Bocanegra, M Ortiz-Rodríguez, IP Garcia-Abadillo… - Biophysica, 2022 - mdpi.com
Over the last few decades, in vitro single-molecule manipulation techniques have enabled
the use of force and displacement as controlled variables in biochemistry. Measuring the …

Unraveling RNA by Mechanical Unzipping

P Rissone, I Pastor, F Ritort - RNA Structure and Function, 2023 - Springer
We review the basic concepts and tools for mechanically unzipping RNA hairpins using
force spectroscopy. By pulling apart the ends of an RNA molecule using optical tweezers, it …

[PDF][PDF] Molecular replica symmetry breaking

F Ritort - Spin glass theory and far beyond, World Scientific, 2022 - ub.edu
A brief overview of mechanical unzipping experiments of single nucleic acids and proteins
shows the power of single-molecule techniques to unravel molecular energy landscapes …